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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDXK All Species: 28.48
Human Site: Y127 Identified Species: 41.78
UniProt: O00764 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00764 NP_003672.1 312 35102 Y127 W D G E G S M Y V P E D L L P
Chimpanzee Pan troglodytes XP_001145080 312 35095 Y127 W D G E G S M Y V P E D L L P
Rhesus Macaque Macaca mulatta XP_001104678 312 34849 Y127 W D G E G S M Y P P S L H S C
Dog Lupus familis XP_544913 345 37964 Y160 W N G E G S M Y V P E D L L P
Cat Felis silvestris
Mouse Mus musculus Q8K183 312 34997 Y127 W N G E G S M Y V P Q D L L P
Rat Rattus norvegicus O35331 312 34890 Y127 W N G E G S M Y V P Q D L L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512013 510 55417 S325 G S M L L P L S K D L P P L L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001119921 305 33891 Y121 L G D N G A M Y V P E N L L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996031 304 33410 G123 Y V C D P V M G D N G Q L Y V
Honey Bee Apis mellifera XP_625042 296 33329 G117 Y V C D P V M G D N G K L Y V
Nematode Worm Caenorhab. elegans O01824 321 35968 D134 G N T T F V C D P V M G D N G
Sea Urchin Strong. purpuratus XP_001192956 264 29158 Y85 Y S H L L T G Y V G S E S F L
Poplar Tree Populus trichocarpa XP_002302951 325 35913 T136 R S I N P K L T Y V C D P V L
Maize Zea mays NP_001149934 310 34024 V120 R S V N P D L V Y V C D P V L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W1X2 309 34025 T120 R S V N P N L T Y V C D P V M
Baker's Yeast Sacchar. cerevisiae P39988 312 35541 D126 G Q L Y V S E D V I P E Y R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93.2 73.9 N.A. 86.2 85.2 N.A. 47.6 N.A. N.A. 72.4 N.A. 46.4 43.5 41.7 45.1
Protein Similarity: 100 100 96.7 83.4 N.A. 93.5 92.6 N.A. 54.1 N.A. N.A. 85.5 N.A. 66.3 68.5 61.9 64.1
P-Site Identity: 100 100 60 93.3 N.A. 86.6 86.6 N.A. 6.6 N.A. N.A. 60 N.A. 13.3 13.3 0 13.3
P-Site Similarity: 100 100 60 100 N.A. 100 100 N.A. 13.3 N.A. N.A. 73.3 N.A. 26.6 26.6 6.6 33.3
Percent
Protein Identity: 46.7 47.1 N.A. 47.7 36.2 N.A.
Protein Similarity: 65.5 68.9 N.A. 69.5 58 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: 20 20 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 13 0 0 0 7 0 0 0 19 0 0 0 7 % C
% Asp: 0 19 7 13 0 7 0 13 13 7 0 50 7 0 0 % D
% Glu: 0 0 0 38 0 0 7 0 0 0 25 13 0 0 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 19 7 38 0 44 0 7 13 0 7 13 7 0 0 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 0 0 7 0 0 7 0 0 7 % K
% Leu: 7 0 7 13 13 0 25 0 0 0 7 7 50 44 25 % L
% Met: 0 0 7 0 0 0 57 0 0 0 7 0 0 0 7 % M
% Asn: 0 25 0 25 0 7 0 0 0 13 0 7 0 7 0 % N
% Pro: 0 0 0 0 32 7 0 0 13 44 7 7 25 0 38 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 13 7 0 0 0 % Q
% Arg: 19 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 0 32 0 0 0 44 0 7 0 0 13 0 7 7 0 % S
% Thr: 0 0 7 7 0 7 0 13 0 0 0 0 0 0 0 % T
% Val: 0 13 13 0 7 19 0 7 50 25 0 0 0 19 13 % V
% Trp: 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 0 0 7 0 0 0 50 19 0 0 0 7 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _