Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCD All Species: 9.09
Human Site: T199 Identified Species: 15.38
UniProt: O00767 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.46
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00767 NP_005054.3 359 41523 T199 A V K E K G S T L D L S D L E
Chimpanzee Pan troglodytes XP_507982 359 41459 T199 A V K E K G S T L D L S D L E
Rhesus Macaque Macaca mulatta XP_001107910 359 41176 T199 A V K E K G A T L D L S D L E
Dog Lupus familis XP_543968 360 41495 L200 A V K E K G G L L D L S D L K
Cat Felis silvestris
Mouse Mus musculus P13011 358 41055 K198 A V K E K G G K L D M S D L K
Rat Rattus norvegicus Q6P7B9 358 40995 K198 A V K E K G G K L D M S D L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513160 386 44199 L226 D V I E K G R L L D M S D L K
Chicken Gallus gallus NP_990221 357 40869 K197 D V I E K G Q K L D L S D L K
Frog Xenopus laevis NP_001087809 339 38710 L180 V I E K G K K L D L S D L K A
Zebra Danio Brachydanio rerio NP_942110 325 37524 K165 E V I E R G R K L E L T D L K
Tiger Blowfish Takifugu rubipres NP_001072046 333 37795 L174 V I E K G K K L D L S D L K A
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790128 331 38349 K172 P D V C E S G K K L D F S D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVZ3 361 42324 P193 T Q R D P H S P T Q G F W F S
Baker's Yeast Sacchar. cerevisiae P21147 510 58384 R237 P N P K Y K A R A D I T D M T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 88 90.5 N.A. 82.4 83 N.A. 68.9 65.7 59.8 58.7 58.2 N.A. N.A. N.A. 50.9
Protein Similarity: 100 99.4 91 95 N.A. 91 91.9 N.A. 79 79.1 74.3 71.8 73.5 N.A. N.A. N.A. 64.6
P-Site Identity: 100 100 93.3 80 N.A. 73.3 73.3 N.A. 60 66.6 0 46.6 0 N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 73.3 73.3 20 73.3 20 N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 26.3 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 44.3 39.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 0 0 0 0 15 0 8 0 0 0 0 0 15 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 0 8 0 0 0 0 15 65 8 15 72 8 0 % D
% Glu: 8 0 15 65 8 0 0 0 0 8 0 0 0 0 22 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 15 0 8 0 % F
% Gly: 0 0 0 0 15 65 29 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 22 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 43 22 58 22 15 36 8 0 0 0 0 15 43 % K
% Leu: 0 0 0 0 0 0 0 29 65 22 43 0 15 65 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 22 0 0 8 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 8 0 8 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 8 0 15 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 22 0 0 0 15 58 8 0 8 % S
% Thr: 8 0 0 0 0 0 0 22 8 0 0 15 0 0 8 % T
% Val: 15 65 8 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _