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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCD All Species: 36.97
Human Site: Y218 Identified Species: 62.56
UniProt: O00767 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00767 NP_005054.3 359 41523 Y218 V M F Q R R Y Y K P G L L M M
Chimpanzee Pan troglodytes XP_507982 359 41459 Y218 V M F Q R R Y Y K T G L L L M
Rhesus Macaque Macaca mulatta XP_001107910 359 41176 Y218 V M F Q R R Y Y K P G L L L M
Dog Lupus familis XP_543968 360 41495 Y219 V M F Q R R Y Y K P G I L L M
Cat Felis silvestris
Mouse Mus musculus P13011 358 41055 Y217 V M F Q R R Y Y K P D L L L M
Rat Rattus norvegicus Q6P7B9 358 40995 Y217 V M F Q R R Y Y K P G L L L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513160 386 44199 Y245 V M F Q R R Y Y K P A V L F M
Chicken Gallus gallus NP_990221 357 40869 Y216 V M F Q R R Y Y K P S V V L L
Frog Xenopus laevis NP_001087809 339 38710 K199 M F Q R R N Y K L S I L V M C
Zebra Danio Brachydanio rerio NP_942110 325 37524 Y184 V M F Q R R F Y K L S V V L M
Tiger Blowfish Takifugu rubipres NP_001072046 333 37795 K193 M F Q R R H Y K L S V V V L C
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790128 331 38349 F191 I V R I Q R K F Y L P F V L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVZ3 361 42324 L212 I F D T S S I L E N C G G E E
Baker's Yeast Sacchar. cerevisiae P21147 510 58384 Y256 I R F Q H R H Y I L L M L L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 88 90.5 N.A. 82.4 83 N.A. 68.9 65.7 59.8 58.7 58.2 N.A. N.A. N.A. 50.9
Protein Similarity: 100 99.4 91 95 N.A. 91 91.9 N.A. 79 79.1 74.3 71.8 73.5 N.A. N.A. N.A. 64.6
P-Site Identity: 100 86.6 93.3 86.6 N.A. 86.6 93.3 N.A. 80 66.6 26.6 60 13.3 N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 100 N.A. 86.6 93.3 46.6 86.6 46.6 N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 26.3 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 44.3 39.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 15 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 8 % E
% Phe: 0 22 72 0 0 0 8 8 0 0 0 8 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 36 8 8 0 0 % G
% His: 0 0 0 0 8 8 8 0 0 0 0 0 0 0 0 % H
% Ile: 22 0 0 8 0 0 8 0 8 0 8 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 15 65 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 15 22 8 43 58 72 15 % L
% Met: 15 65 0 0 0 0 0 0 0 0 0 8 0 15 58 % M
% Asn: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 50 8 0 0 0 0 % P
% Gln: 0 0 15 72 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 15 79 79 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 0 0 15 15 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 8 % T
% Val: 65 8 0 0 0 0 0 0 0 0 8 29 36 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 72 72 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _