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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAP2A All Species: 13.33
Human Site: T32 Identified Species: 22.56
UniProt: O14494 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14494 NP_003702.2 284 32156 T32 A I L T S R H T P F Q R G V F
Chimpanzee Pan troglodytes XP_517759 284 32152 T32 A I L T S R H T P F Q R G V F
Rhesus Macaque Macaca mulatta XP_001116998 289 31981 A30 A I L T L V N A P Y K R G F Y
Dog Lupus familis XP_849687 215 24386
Cat Felis silvestris
Mouse Mus musculus Q61469 283 31873 T32 A I L T S R H T P F Q R G I F
Rat Rattus norvegicus O08564 282 31978 T32 I I L T S R H T P F Q R G V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513815 435 48425 K91 V L N L A K I K P Y Q R G F F
Chicken Gallus gallus XP_424730 246 27534
Frog Xenopus laevis Q6GM05 314 34960 P51 Y D S S Y T K P Y P G P D E S
Zebra Danio Brachydanio rerio Q6IQH6 333 36474 P57 N D A D L L K P Y P G P E E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V576 379 42771 E123 R G F F C D D E S L K H P F H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10022 341 39009 G49 V I V P T L L G V S Q R G F F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XI60 290 32684 L30 M H D W L I L L L L I V I E I
Baker's Yeast Sacchar. cerevisiae Q05521 289 33495 L30 F L L I I M I L L N Y P V Y Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 53.2 68.6 N.A. 82.7 83 N.A. 20 72.1 27 27.3 N.A. 34.8 N.A. 28.4 N.A.
Protein Similarity: 100 100 68.5 72.8 N.A. 91.5 90.4 N.A. 33.3 80.2 48.7 46.2 N.A. 48.5 N.A. 46.6 N.A.
P-Site Identity: 100 100 46.6 0 N.A. 93.3 93.3 N.A. 33.3 0 0 0 N.A. 0 N.A. 33.3 N.A.
P-Site Similarity: 100 100 73.3 0 N.A. 100 93.3 N.A. 60 0 6.6 0 N.A. 6.6 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.1 25.6 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 8 0 8 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 8 8 0 8 8 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 0 8 22 0 % E
% Phe: 8 0 8 8 0 0 0 0 0 29 0 0 0 29 43 % F
% Gly: 0 8 0 0 0 0 0 8 0 0 15 0 50 0 0 % G
% His: 0 8 0 0 0 0 29 0 0 0 0 8 0 0 8 % H
% Ile: 8 43 0 8 8 8 15 0 0 0 8 0 8 8 8 % I
% Lys: 0 0 0 0 0 8 15 8 0 0 15 0 0 0 0 % K
% Leu: 0 15 43 8 22 15 15 15 15 15 0 0 0 0 0 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 0 0 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 15 43 15 0 22 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % Q
% Arg: 8 0 0 0 0 29 0 0 0 0 0 50 0 0 0 % R
% Ser: 0 0 8 8 29 0 0 0 8 8 0 0 0 0 15 % S
% Thr: 0 0 0 36 8 8 0 29 0 0 0 0 0 0 0 % T
% Val: 15 0 8 0 0 8 0 0 8 0 0 8 8 22 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 0 15 15 8 0 0 8 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _