KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2A
All Species:
24.24
Human Site:
T53
Identified Species:
41.03
UniProt:
O14494
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14494
NP_003702.2
284
32156
T53
K
Y
P
Y
K
E
D
T
I
P
Y
A
L
L
G
Chimpanzee
Pan troglodytes
XP_517759
284
32152
T53
K
Y
P
Y
K
E
D
T
I
P
Y
A
L
L
G
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
T51
R
Y
P
Y
R
P
D
T
I
T
H
G
V
M
A
Dog
Lupus familis
XP_849687
215
24386
Cat
Felis silvestris
Mouse
Mus musculus
Q61469
283
31873
T53
K
Y
P
Y
K
E
D
T
I
P
Y
A
L
L
G
Rat
Rattus norvegicus
O08564
282
31978
T53
K
Y
P
Y
R
E
D
T
I
P
Y
A
L
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513815
435
48425
T112
K
Y
P
F
H
D
S
T
I
T
S
T
V
L
Y
Chicken
Gallus gallus
XP_424730
246
27534
L19
L
D
V
V
C
V
V
L
A
G
L
P
F
A
I
Frog
Xenopus laevis
Q6GM05
314
34960
G72
L
L
L
S
L
V
T
G
V
P
V
L
V
I
I
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
A78
I
L
Y
C
V
V
A
A
A
P
T
A
I
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
A144
W
M
L
Y
F
I
G
A
V
I
P
V
G
V
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
T70
R
Y
E
Y
R
K
D
T
I
T
A
V
Q
L
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
E51
P
F
H
R
F
V
G
E
D
M
L
T
D
L
R
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
T51
Q
F
Y
I
N
D
L
T
I
S
H
P
Y
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
53.2
68.6
N.A.
82.7
83
N.A.
20
72.1
27
27.3
N.A.
34.8
N.A.
28.4
N.A.
Protein Similarity:
100
100
68.5
72.8
N.A.
91.5
90.4
N.A.
33.3
80.2
48.7
46.2
N.A.
48.5
N.A.
46.6
N.A.
P-Site Identity:
100
100
40
0
N.A.
100
93.3
N.A.
40
0
6.6
13.3
N.A.
6.6
N.A.
40
N.A.
P-Site Similarity:
100
100
73.3
0
N.A.
100
100
N.A.
60
0
26.6
26.6
N.A.
20
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
15
15
0
8
36
0
15
8
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
15
43
0
8
0
0
0
8
0
0
% D
% Glu:
0
0
8
0
0
29
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
15
0
8
15
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
0
0
0
0
15
8
0
8
0
8
8
0
29
% G
% His:
0
0
8
0
8
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
58
8
0
0
8
15
22
% I
% Lys:
36
0
0
0
22
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
15
15
0
8
0
8
8
0
0
15
8
29
50
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
43
0
0
8
0
0
0
43
8
15
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
15
0
0
8
22
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
8
0
0
8
0
0
8
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
58
0
22
8
15
0
0
8
% T
% Val:
0
0
8
8
8
29
8
0
15
0
8
15
22
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
15
50
0
0
0
0
0
0
29
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _