KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2A
All Species:
17.27
Human Site:
Y147
Identified Species:
29.23
UniProt:
O14494
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14494
NP_003702.2
284
32156
Y147
K
I
N
C
S
D
G
Y
I
E
Y
Y
I
C
R
Chimpanzee
Pan troglodytes
XP_517759
284
32152
Y147
K
I
N
C
S
D
G
Y
I
E
Y
Y
I
C
R
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
V144
R
V
N
C
S
V
Y
V
Q
L
E
K
V
C
R
Dog
Lupus familis
XP_849687
215
24386
N80
C
S
V
G
Y
V
E
N
Y
I
C
Q
G
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61469
283
31873
Y147
K
I
N
C
S
D
G
Y
I
E
D
Y
I
C
Q
Rat
Rattus norvegicus
O08564
282
31978
Y147
K
I
N
C
S
D
G
Y
I
E
N
F
V
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513815
435
48425
H266
S
V
Y
Y
N
H
L
H
S
N
S
F
V
R
N
Chicken
Gallus gallus
XP_424730
246
27534
A111
T
F
I
F
G
A
A
A
S
Q
S
L
T
D
I
Frog
Xenopus laevis
Q6GM05
314
34960
I169
C
R
Q
F
T
Q
F
I
T
D
A
N
A
C
T
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
I175
C
H
F
S
H
Q
F
I
A
N
G
N
I
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
Y244
D
A
I
N
A
G
K
Y
I
Q
E
F
T
C
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
Y173
V
T
G
D
S
H
R
Y
I
T
D
Y
T
C
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
V143
G
I
G
I
F
H
N
V
T
K
N
V
L
C
T
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
T145
L
P
L
D
T
L
F
T
A
K
D
V
C
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
53.2
68.6
N.A.
82.7
83
N.A.
20
72.1
27
27.3
N.A.
34.8
N.A.
28.4
N.A.
Protein Similarity:
100
100
68.5
72.8
N.A.
91.5
90.4
N.A.
33.3
80.2
48.7
46.2
N.A.
48.5
N.A.
46.6
N.A.
P-Site Identity:
100
100
33.3
0
N.A.
86.6
73.3
N.A.
0
0
6.6
13.3
N.A.
20
N.A.
33.3
N.A.
P-Site Similarity:
100
100
53.3
0
N.A.
93.3
93.3
N.A.
33.3
6.6
20
13.3
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
8
15
0
8
0
8
0
8
% A
% Cys:
22
0
0
36
0
0
0
0
0
0
8
0
8
72
0
% C
% Asp:
8
0
0
15
0
29
0
0
0
8
22
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
29
15
0
0
0
0
% E
% Phe:
0
8
8
15
8
0
22
0
0
0
0
22
0
0
0
% F
% Gly:
8
0
15
8
8
8
29
0
0
0
8
0
8
0
0
% G
% His:
0
8
0
0
8
22
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
36
15
8
0
0
0
15
43
8
0
0
29
0
8
% I
% Lys:
29
0
0
0
0
0
8
0
0
15
0
8
0
0
8
% K
% Leu:
8
0
8
0
0
8
8
0
0
8
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
36
8
8
0
8
8
0
15
15
15
0
8
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
15
0
0
8
15
0
8
0
0
15
% Q
% Arg:
8
8
0
0
0
0
8
0
0
0
0
0
0
8
22
% R
% Ser:
8
8
0
8
43
0
0
0
15
0
15
0
0
0
0
% S
% Thr:
8
8
0
0
15
0
0
8
15
8
0
0
22
8
36
% T
% Val:
8
15
8
0
0
15
0
15
0
0
0
15
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
8
43
8
0
15
29
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _