KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2A
All Species:
28.18
Human Site:
Y185
Identified Species:
47.69
UniProt:
O14494
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14494
NP_003702.2
284
32156
Y185
C
M
L
F
V
A
L
Y
L
Q
A
R
M
K
G
Chimpanzee
Pan troglodytes
XP_517759
284
32152
Y185
C
M
L
F
V
A
L
Y
L
Q
A
R
M
K
G
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
S182
C
M
L
F
L
A
V
S
L
F
L
Q
G
L
L
Dog
Lupus familis
XP_849687
215
24386
A118
F
V
A
L
Y
L
Q
A
R
M
K
G
D
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61469
283
31873
Y185
C
M
L
F
V
A
L
Y
L
Q
A
R
M
K
G
Rat
Rattus norvegicus
O08564
282
31978
Y185
C
M
L
F
V
A
L
Y
L
Q
A
R
M
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513815
435
48425
I304
T
D
I
A
K
Y
S
I
G
R
L
R
P
H
F
Chicken
Gallus gallus
XP_424730
246
27534
E149
N
C
S
L
G
Y
I
E
N
I
P
C
Q
G
D
Frog
Xenopus laevis
Q6GM05
314
34960
Y207
A
A
L
Y
L
A
M
Y
I
T
S
T
I
K
A
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
Y213
S
A
V
Y
V
T
M
Y
I
T
S
T
I
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
L282
T
F
F
A
M
V
Y
L
A
L
Y
L
Q
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
Y211
C
A
T
W
S
A
L
Y
I
Q
A
R
L
G
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
Y181
G
L
G
F
L
S
L
Y
L
S
G
K
I
R
V
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
W183
G
L
G
Y
L
Y
F
W
L
C
G
Q
L
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
53.2
68.6
N.A.
82.7
83
N.A.
20
72.1
27
27.3
N.A.
34.8
N.A.
28.4
N.A.
Protein Similarity:
100
100
68.5
72.8
N.A.
91.5
90.4
N.A.
33.3
80.2
48.7
46.2
N.A.
48.5
N.A.
46.6
N.A.
P-Site Identity:
100
100
40
0
N.A.
100
100
N.A.
6.6
0
26.6
20
N.A.
0
N.A.
46.6
N.A.
P-Site Similarity:
100
100
60
6.6
N.A.
100
100
N.A.
20
6.6
66.6
60
N.A.
6.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
8
15
0
50
0
8
8
0
36
0
0
8
15
% A
% Cys:
43
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
8
8
43
0
0
8
0
0
8
0
0
0
0
8
% F
% Gly:
15
0
15
0
8
0
0
0
8
0
15
8
8
15
29
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
8
8
22
8
0
0
22
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
8
8
0
43
0
% K
% Leu:
0
15
43
15
29
8
43
8
50
8
15
8
15
15
8
% L
% Met:
0
36
0
0
8
0
15
0
0
8
0
0
29
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
36
0
15
15
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
43
0
8
8
% R
% Ser:
8
0
8
0
8
8
8
8
0
8
15
0
0
0
0
% S
% Thr:
15
0
8
0
0
8
0
0
0
15
0
15
0
0
15
% T
% Val:
0
8
8
0
36
8
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
22
8
22
8
58
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _