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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2B
All Species:
20.3
Human Site:
T282
Identified Species:
34.36
UniProt:
O14495
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14495
NP_003704.3
311
35116
T282
S
D
L
F
K
T
K
T
T
L
S
L
P
A
P
Chimpanzee
Pan troglodytes
XP_001146001
285
32146
E262
T
T
F
K
E
R
K
E
E
D
S
H
T
T
L
Rhesus Macaque
Macaca mulatta
XP_001114350
311
34980
T282
S
D
L
F
K
T
K
T
T
L
S
L
P
A
P
Dog
Lupus familis
XP_536696
312
35165
T283
S
D
L
F
K
T
K
T
T
L
S
L
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY8
312
35198
T283
S
D
L
F
K
T
K
T
S
L
S
L
P
A
P
Rat
Rattus norvegicus
P97544
312
35300
T283
S
D
L
F
K
T
K
T
T
L
S
L
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519347
257
28776
K235
I
S
S
M
F
R
S
K
K
R
S
A
L
F
S
Chicken
Gallus gallus
NP_001123960
313
35047
P284
S
D
L
F
K
P
K
P
K
T
C
L
P
P
P
Frog
Xenopus laevis
Q6GM05
314
34960
R276
V
N
N
F
K
G
R
R
T
E
H
E
H
W
P
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
G280
C
V
V
N
N
F
K
G
T
H
S
T
P
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
N354
S
D
L
F
Q
K
P
N
T
K
P
Y
L
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
T286
N
N
S
T
E
S
E
T
Q
P
L
L
L
P
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
N268
Q
M
L
A
D
S
R
N
D
V
Q
D
S
A
G
Baker's Yeast
Sacchar. cerevisiae
Q04396
274
31568
Y252
V
L
A
F
L
V
I
Y
C
C
W
K
W
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.6
95.5
96.4
N.A.
94.5
94.2
N.A.
50.1
83
26.4
24.6
N.A.
35
N.A.
28.4
N.A.
Protein Similarity:
100
59.8
98.3
98
N.A.
97.7
97.7
N.A.
63.9
90
47.1
42.6
N.A.
50.6
N.A.
45.7
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
100
N.A.
6.6
60
26.6
26.6
N.A.
40
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
100
N.A.
6.6
60
40
33.3
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
0
8
0
43
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% C
% Asp:
0
50
0
0
8
0
0
0
8
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
15
0
8
8
8
8
0
8
0
0
0
% E
% Phe:
0
0
8
65
8
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
8
8
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
50
8
58
8
15
8
0
8
0
0
8
% K
% Leu:
0
8
58
0
8
0
0
0
0
36
8
50
22
0
8
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
15
8
8
8
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
8
0
8
8
0
50
22
50
% P
% Gln:
8
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
15
8
0
8
0
0
0
0
15
% R
% Ser:
50
8
15
0
0
15
8
0
8
0
58
0
8
0
8
% S
% Thr:
8
8
0
8
0
36
0
43
50
8
0
8
8
22
0
% T
% Val:
15
8
8
0
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _