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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAP2B All Species: 28.48
Human Site: Y62 Identified Species: 48.21
UniProt: O14495 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14495 NP_003704.3 311 35116 Y62 E T S T I K P Y H R G F Y C N
Chimpanzee Pan troglodytes XP_001146001 285 32146 D52 S I N Y P Y H D S T V T S T V
Rhesus Macaque Macaca mulatta XP_001114350 311 34980 Y62 E T S T I K P Y H R G F Y C N
Dog Lupus familis XP_536696 312 35165 Y62 E T S T I K P Y H R G F Y C N
Cat Felis silvestris
Mouse Mus musculus Q99JY8 312 35198 Y62 E T S T I K P Y R R G F Y C N
Rat Rattus norvegicus P97544 312 35300 Y62 E T S T I K P Y R R G F Y C N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519347 257 28776 I26 F Y C N D S S I R Y P L K R V
Chicken Gallus gallus NP_001123960 313 35047 Y62 E T S T I Q P Y Q R G F Y C D
Frog Xenopus laevis Q6GM05 314 34960 Y52 D S S Y T K P Y P G P D E S S
Zebra Danio Brachydanio rerio Q6IQH6 333 36474 Y58 D A D L L K P Y P G P E E S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V576 379 42771 Y114 F F L L G E P Y K R G F F C D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10022 341 39009 F56 G V S Q R G F F C D D D S I R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XI60 290 32684 D56 V G E D M L T D L R Y P L Q D
Baker's Yeast Sacchar. cerevisiae Q04396 274 31568 G42 E I S L V P R G Q N I E F S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.6 95.5 96.4 N.A. 94.5 94.2 N.A. 50.1 83 26.4 24.6 N.A. 35 N.A. 28.4 N.A.
Protein Similarity: 100 59.8 98.3 98 N.A. 97.7 97.7 N.A. 63.9 90 47.1 42.6 N.A. 50.6 N.A. 45.7 N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 0 80 26.6 20 N.A. 40 N.A. 6.6 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 0 93.3 46.6 40 N.A. 60 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.6 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. 42.1 43.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 8 0 0 0 0 50 0 % C
% Asp: 15 0 8 8 8 0 0 15 0 8 8 15 0 0 22 % D
% Glu: 50 0 8 0 0 8 0 0 0 0 0 15 15 0 0 % E
% Phe: 15 8 0 0 0 0 8 8 0 0 0 50 15 0 0 % F
% Gly: 8 8 0 0 8 8 0 8 0 15 50 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 22 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 43 0 0 8 0 0 8 0 0 8 0 % I
% Lys: 0 0 0 0 0 50 0 0 8 0 0 0 8 0 0 % K
% Leu: 0 0 8 22 8 8 0 0 8 0 0 8 8 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 36 % N
% Pro: 0 0 0 0 8 8 65 0 15 0 22 8 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 0 15 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 8 0 8 0 22 58 0 0 0 8 8 % R
% Ser: 8 8 65 0 0 8 8 0 8 0 0 0 15 22 15 % S
% Thr: 0 43 0 43 8 0 8 0 0 8 0 8 0 8 0 % T
% Val: 8 8 0 0 8 0 0 0 0 0 8 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 15 0 8 0 65 0 8 8 0 43 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _