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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2B
All Species:
22.42
Human Site:
Y75
Identified Species:
37.95
UniProt:
O14495
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14495
NP_003704.3
311
35116
Y75
C
N
D
E
S
I
K
Y
P
L
K
T
G
E
T
Chimpanzee
Pan troglodytes
XP_001146001
285
32146
V65
T
V
L
I
L
V
G
V
G
L
P
I
S
S
I
Rhesus Macaque
Macaca mulatta
XP_001114350
311
34980
Y75
C
N
D
E
S
I
K
Y
P
L
K
T
G
E
T
Dog
Lupus familis
XP_536696
312
35165
Y75
C
N
D
E
S
I
K
Y
P
L
K
I
G
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY8
312
35198
Y75
C
N
D
E
S
I
K
Y
P
L
K
V
S
E
T
Rat
Rattus norvegicus
P97544
312
35300
Y75
C
N
D
E
S
I
K
Y
P
L
K
V
S
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519347
257
28776
T39
R
V
E
T
V
S
D
T
V
L
I
S
V
G
I
Chicken
Gallus gallus
NP_001123960
313
35047
Y75
C
D
D
D
S
I
R
Y
P
L
K
S
M
E
T
Frog
Xenopus laevis
Q6GM05
314
34960
L65
S
S
D
I
P
P
V
L
L
L
S
L
V
T
G
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
I71
S
S
F
I
Q
P
L
I
L
Y
C
V
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
H127
C
D
D
E
S
L
K
H
P
F
H
D
S
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
D69
I
R
Y
E
Y
R
K
D
T
I
T
A
V
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
W69
Q
D
N
T
I
P
F
W
A
V
P
L
I
A
V
Baker's Yeast
Sacchar. cerevisiae
Q04396
274
31568
S55
S
L
D
D
P
S
I
S
K
R
Y
V
P
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.6
95.5
96.4
N.A.
94.5
94.2
N.A.
50.1
83
26.4
24.6
N.A.
35
N.A.
28.4
N.A.
Protein Similarity:
100
59.8
98.3
98
N.A.
97.7
97.7
N.A.
63.9
90
47.1
42.6
N.A.
50.6
N.A.
45.7
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
86.6
N.A.
6.6
66.6
13.3
0
N.A.
40
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
86.6
N.A.
20
93.3
20
6.6
N.A.
60
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
8
0
15
8
% A
% Cys:
50
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
22
65
15
0
0
8
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
50
0
0
0
0
0
0
0
0
0
43
8
% E
% Phe:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
0
0
22
8
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
22
8
43
8
8
0
8
8
15
8
0
15
% I
% Lys:
0
0
0
0
0
0
50
0
8
0
43
0
0
0
0
% K
% Leu:
0
8
8
0
8
8
8
8
15
65
0
15
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
36
8
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
15
22
0
0
50
0
15
0
8
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
8
0
0
0
8
8
0
0
8
0
0
0
0
0
% R
% Ser:
22
15
0
0
50
15
0
8
0
0
8
15
29
8
0
% S
% Thr:
8
0
0
15
0
0
0
8
8
0
8
15
0
15
43
% T
% Val:
0
15
0
0
8
8
8
8
8
8
0
29
29
0
15
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
43
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _