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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BHLHE40
All Species:
26.06
Human Site:
T226
Identified Species:
57.33
UniProt:
O14503
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14503
NP_003661.1
412
45510
T226
C
V
P
V
I
Q
R
T
F
A
H
S
S
G
E
Chimpanzee
Pan troglodytes
XP_516248
608
65471
T422
C
V
P
V
I
Q
R
T
F
A
H
S
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001095506
421
46542
T235
C
V
P
V
I
Q
R
T
F
A
H
S
S
G
E
Dog
Lupus familis
XP_541795
412
45458
T226
C
V
P
V
I
Q
R
T
F
A
H
S
S
G
E
Cat
Felis silvestris
Mouse
Mus musculus
O35185
411
45342
T226
C
V
P
V
I
Q
R
T
F
A
P
S
G
G
E
Rat
Rattus norvegicus
O35780
411
45511
T226
C
V
P
V
I
Q
R
T
F
A
P
S
G
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507326
577
63175
T391
C
V
P
V
I
Q
R
T
F
A
N
S
S
G
E
Chicken
Gallus gallus
O57337
290
31053
L108
L
S
A
D
P
S
V
L
G
K
Y
R
A
G
F
Frog
Xenopus laevis
Q90Z12
281
30197
A98
L
Q
R
V
Q
M
T
A
A
L
T
S
D
P
S
Zebra Danio
Brachydanio rerio
NP_997844
403
44654
P219
G
H
A
K
N
C
V
P
V
I
Q
R
T
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121958
400
44609
L204
Q
Q
H
C
E
K
I
L
A
T
S
D
R
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.9
91.6
95.8
N.A.
90.2
89.8
N.A.
58.5
23
22.8
60.4
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
100
66.2
92.8
96.8
N.A.
92.9
92.9
N.A.
63.2
38.1
39
74.7
N.A.
N.A.
38.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
6.6
13.3
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
100
20
13.3
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
10
19
64
0
0
10
0
0
% A
% Cys:
64
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
64
% E
% Phe:
0
0
0
0
0
0
0
0
64
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
10
0
0
0
19
73
10
% G
% His:
0
10
10
0
0
0
0
0
0
0
37
0
0
0
0
% H
% Ile:
0
0
0
0
64
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
10
0
0
0
10
0
0
0
0
0
% K
% Leu:
19
0
0
0
0
0
0
19
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
64
0
10
0
0
10
0
0
19
0
0
10
10
% P
% Gln:
10
19
0
0
10
64
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
64
0
0
0
0
19
10
0
0
% R
% Ser:
0
10
0
0
0
10
0
0
0
0
10
73
46
0
10
% S
% Thr:
0
0
0
0
0
0
10
64
0
10
10
0
10
0
0
% T
% Val:
0
64
0
73
0
0
19
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _