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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2AP1
All Species:
12.42
Human Site:
S21
Identified Species:
27.33
UniProt:
O14519
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14519
NP_004633.1
115
12365
S21
A
A
L
N
A
A
G
S
V
H
S
P
S
T
S
Chimpanzee
Pan troglodytes
XP_509460
368
38806
S274
C
R
G
G
L
A
G
S
V
H
S
P
S
T
S
Rhesus Macaque
Macaca mulatta
XP_001100820
132
14711
G38
G
G
Q
K
R
R
A
G
S
V
H
S
P
S
T
Dog
Lupus familis
XP_533015
115
12485
S21
A
S
L
S
A
A
G
S
V
H
P
P
S
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPY4
127
13183
V31
P
V
P
T
A
G
S
V
P
S
P
S
G
S
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507129
107
11485
T19
G
S
V
H
S
P
S
T
S
M
A
S
S
T
Q
Chicken
Gallus gallus
NP_001034353
90
9895
Frog
Xenopus laevis
NP_001080857
116
12629
S22
N
P
G
L
Q
A
G
S
A
H
S
P
S
T
S
Zebra Danio
Brachydanio rerio
NP_001009898
111
11871
G19
G
S
N
H
T
P
P
G
S
C
G
S
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572688
281
29242
L187
L
N
L
S
S
S
Q
L
K
Y
P
P
P
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795338
231
24671
V137
Y
A
G
G
R
T
H
V
H
A
S
K
S
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.1
75
94.7
N.A.
58.2
N.A.
N.A.
82.6
72.1
78.4
59.1
N.A.
25.6
N.A.
N.A.
31.6
Protein Similarity:
100
30.9
78
96.5
N.A.
70
N.A.
N.A.
91.3
74.7
87
73
N.A.
32.3
N.A.
N.A.
41.1
P-Site Identity:
100
66.6
0
80
N.A.
6.6
N.A.
N.A.
13.3
0
60
13.3
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
66.6
13.3
93.3
N.A.
13.3
N.A.
N.A.
53.3
0
60
26.6
N.A.
53.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
0
0
28
37
10
0
10
10
10
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
10
28
19
0
10
37
19
0
0
10
0
10
0
10
% G
% His:
0
0
0
19
0
0
10
0
10
37
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
10
0
10
0
% K
% Leu:
10
0
28
10
10
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
0
0
19
10
0
10
0
28
46
19
10
0
% P
% Gln:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
19
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
28
0
19
19
10
19
37
28
10
37
37
64
28
46
% S
% Thr:
0
0
0
10
10
10
0
10
0
0
0
0
0
46
19
% T
% Val:
0
10
10
0
0
0
0
19
28
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _