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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK2AP1 All Species: 19.09
Human Site: S28 Identified Species: 42
UniProt: O14519 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14519 NP_004633.1 115 12365 S28 S V H S P S T S M A T S S Q Y
Chimpanzee Pan troglodytes XP_509460 368 38806 S281 S V H S P S T S M A T S S Q Y
Rhesus Macaque Macaca mulatta XP_001100820 132 14711 T45 G S V H S P S T S M A S S Q Y
Dog Lupus familis XP_533015 115 12485 S28 S V H P P S T S M A T S S Q Y
Cat Felis silvestris
Mouse Mus musculus Q9CPY4 127 13183 V38 V P S P S G S V P G A A A P F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507129 107 11485 Q26 T S M A S S T Q Y R Q L I N D
Chicken Gallus gallus NP_001034353 90 9895 Y14 Y R Q L I N D Y G P P S L G Y
Frog Xenopus laevis NP_001080857 116 12629 S29 S A H S P S T S M V S T A Q Y
Zebra Danio Brachydanio rerio NP_001009898 111 11871 S26 G S C G S S P S L A S S S N F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572688 281 29242 T194 L K Y P P P S T S P V V V T T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795338 231 24671 G144 V H A S K S K G S T R T D R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.1 75 94.7 N.A. 58.2 N.A. N.A. 82.6 72.1 78.4 59.1 N.A. 25.6 N.A. N.A. 31.6
Protein Similarity: 100 30.9 78 96.5 N.A. 70 N.A. N.A. 91.3 74.7 87 73 N.A. 32.3 N.A. N.A. 41.1
P-Site Identity: 100 100 26.6 93.3 N.A. 0 N.A. N.A. 13.3 13.3 66.6 33.3 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 40 93.3 N.A. 26.6 N.A. N.A. 26.6 20 86.6 53.3 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 0 0 0 37 19 10 19 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % F
% Gly: 19 0 0 10 0 10 0 10 10 10 0 0 0 10 0 % G
% His: 0 10 37 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 10 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 10 0 0 0 0 10 0 0 10 10 0 0 % L
% Met: 0 0 10 0 0 0 0 0 37 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 10 0 28 46 19 10 0 10 19 10 0 0 10 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 10 0 0 46 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 10 0 0 10 10 % R
% Ser: 37 28 10 37 37 64 28 46 28 0 19 55 46 0 0 % S
% Thr: 10 0 0 0 0 0 46 19 0 10 28 19 0 10 10 % T
% Val: 19 28 10 0 0 0 0 10 0 10 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 0 0 10 10 0 0 0 0 0 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _