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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2AP1
All Species:
20.3
Human Site:
Y42
Identified Species:
44.67
UniProt:
O14519
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14519
NP_004633.1
115
12365
Y42
Y
R
Q
L
L
S
D
Y
G
P
P
S
L
G
Y
Chimpanzee
Pan troglodytes
XP_509460
368
38806
Y295
Y
R
Q
L
L
S
D
Y
G
P
P
S
L
G
Y
Rhesus Macaque
Macaca mulatta
XP_001100820
132
14711
Y59
Y
R
Q
L
L
S
D
Y
G
P
P
S
L
G
Y
Dog
Lupus familis
XP_533015
115
12485
Y42
Y
R
Q
L
L
S
D
Y
R
P
P
S
L
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPY4
127
13183
F52
F
R
P
L
F
N
D
F
G
P
P
S
M
G
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507129
107
11485
G40
D
Y
G
P
P
S
L
G
Y
T
Q
G
S
G
S
Chicken
Gallus gallus
NP_001034353
90
9895
T28
Y
T
Q
G
I
Q
G
T
S
S
S
Q
V
P
Q
Frog
Xenopus laevis
NP_001080857
116
12629
Y43
Y
R
Q
L
V
N
D
Y
G
P
P
S
L
G
Y
Zebra Danio
Brachydanio rerio
NP_001009898
111
11871
F40
F
R
P
A
F
S
D
F
G
P
P
S
M
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572688
281
29242
T208
T
Q
T
S
A
N
I
T
T
P
L
T
S
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795338
231
24671
L158
R
P
F
F
S
G
T
L
N
A
A
A
V
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.1
75
94.7
N.A.
58.2
N.A.
N.A.
82.6
72.1
78.4
59.1
N.A.
25.6
N.A.
N.A.
31.6
Protein Similarity:
100
30.9
78
96.5
N.A.
70
N.A.
N.A.
91.3
74.7
87
73
N.A.
32.3
N.A.
N.A.
41.1
P-Site Identity:
100
100
100
93.3
N.A.
60
N.A.
N.A.
13.3
13.3
86.6
53.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
13.3
26.6
100
80
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
0
10
10
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
19
0
10
10
19
0
0
19
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
10
0
10
10
10
55
0
0
10
0
73
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
55
37
0
10
10
0
0
10
0
46
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% M
% Asn:
0
0
0
0
0
28
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
10
19
10
10
0
0
0
0
73
64
0
0
10
0
% P
% Gln:
0
10
55
0
0
10
0
0
0
0
10
10
0
0
19
% Q
% Arg:
10
64
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
10
55
0
0
10
10
10
64
19
0
10
% S
% Thr:
10
10
10
0
0
0
10
19
10
10
0
10
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
55
10
0
0
0
0
0
46
10
0
0
0
0
0
55
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _