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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AQP7 All Species: 9.09
Human Site: S325 Identified Species: 20
UniProt: O14520 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14520 NP_001161.1 342 37232 S325 S V S P A N R S S V H P A P P
Chimpanzee Pan troglodytes XP_520531 292 31527 S275 H L E Q P P P S N E E E N V K
Rhesus Macaque Macaca mulatta XP_001100020 342 37230 S325 S V S P A N R S S V H P A P P
Dog Lupus familis XP_531973 341 37378 P324 S V S P A N R P L A Q T V P P
Cat Felis silvestris
Mouse Mus musculus O54794 303 32648 K287 Q K V T A S Y K N A A S A N I
Rat Rattus norvegicus P56403 269 28863 G253 L L G A Y L G G I V Y L G L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512694 292 31482 S275 H M E A P P P S T E Q E N V K
Chicken Gallus gallus XP_424498 304 32805 L288 D I H N Q P V L E R G N E K G
Frog Xenopus laevis NP_001087946 292 31749 S275 H I E P V P Q S T E Q E N I K
Zebra Danio Brachydanio rerio NP_956204 303 32332 E287 T R P A V D P E C I P L D K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9ATN4 282 29541 S266 P L R E I T K S T S F L K S T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.7 96.1 73.3 N.A. 64.9 61.7 N.A. 40 49.7 40.9 44.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.3 97.9 82.7 N.A. 76 70.7 N.A. 59.3 61.1 58.4 63.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 60 N.A. 13.3 6.6 N.A. 6.6 0 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 60 N.A. 26.6 20 N.A. 20 6.6 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 20.7 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 34.5 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 28 37 0 0 0 0 19 10 0 28 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 28 10 0 0 0 10 10 28 10 28 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 10 0 0 10 0 10 0 10 % G
% His: 28 0 10 0 0 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 19 0 0 10 0 0 0 10 10 0 0 0 10 19 % I
% Lys: 0 10 0 0 0 0 10 10 0 0 0 0 10 19 28 % K
% Leu: 10 28 0 0 0 10 0 10 10 0 0 28 0 10 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 28 0 0 19 0 0 10 28 10 0 % N
% Pro: 10 0 10 37 19 37 28 10 0 0 10 19 0 28 28 % P
% Gln: 10 0 0 10 10 0 10 0 0 0 28 0 0 0 0 % Q
% Arg: 0 10 10 0 0 0 28 0 0 10 0 0 0 0 0 % R
% Ser: 28 0 28 0 0 10 0 55 19 10 0 10 0 10 0 % S
% Thr: 10 0 0 10 0 10 0 0 28 0 0 10 0 0 10 % T
% Val: 0 28 10 0 19 0 10 0 0 28 0 0 10 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _