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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDHD All Species: 19.7
Human Site: S32 Identified Species: 39.39
UniProt: O14521 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14521 NP_002993.1 159 17043 S32 V V R P A H I S A F L Q D R P
Chimpanzee Pan troglodytes XP_508756 159 17009 S32 V V R P A H I S A F L Q D R P
Rhesus Macaque Macaca mulatta XP_001093794 159 17136 S32 V V R P A H I S A F L Q D R P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CXV1 159 16995 S32 V V R P A Y V S A F L Q D Q P
Rat Rattus norvegicus Q6PCT8 159 16957 S32 A V R P A F V S A F L Q D Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIS0 157 16417 L33 L L R H S A V L T A A A D R S
Frog Xenopus laevis Q6AZV0 152 16380 Q32 R P L P C L S Q D L H M V Q T
Zebra Danio Brachydanio rerio Q68FN7 158 16954 Q32 L I R P L A V Q Q K D H D C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCI5 182 19282 V34 L K S Y S T L V A N V Q R K A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O62215 145 15746 T33 T I V R A T S T L N D G A S K
Sea Urchin Strong. purpuratus XP_792876 148 16234 M34 Y Q A N Y P A M L N T L H T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGY6 166 17657 T32 L R V A A F H T T S R K S L L
Conservation
Percent
Protein Identity: 100 98.7 96.2 N.A. N.A. 82.3 81.1 N.A. N.A. 60.3 64.7 59.1 N.A. 29.6 N.A. 33.9 44.6
Protein Similarity: 100 100 97.4 N.A. N.A. 88.6 87.4 N.A. N.A. 67.9 74.8 71 N.A. 47.2 N.A. 45.9 63.5
P-Site Identity: 100 100 100 N.A. N.A. 80 73.3 N.A. N.A. 20 6.6 20 N.A. 13.3 N.A. 6.6 0
P-Site Similarity: 100 100 100 N.A. N.A. 100 86.6 N.A. N.A. 46.6 13.3 40 N.A. 46.6 N.A. 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 30.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41.5
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 59 17 9 0 50 9 9 9 9 0 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 17 0 59 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 17 0 0 0 42 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 9 0 25 9 0 0 0 9 9 9 0 0 % H
% Ile: 0 17 0 0 0 0 25 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 9 0 9 0 9 9 % K
% Leu: 34 9 9 0 9 9 9 9 17 9 42 9 0 9 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 25 0 0 0 0 0 % N
% Pro: 0 9 0 59 0 9 0 0 0 0 0 0 0 0 42 % P
% Gln: 0 9 0 0 0 0 0 17 9 0 0 50 0 25 0 % Q
% Arg: 9 9 59 9 0 0 0 0 0 0 9 0 9 34 0 % R
% Ser: 0 0 9 0 17 0 17 42 0 9 0 0 9 9 17 % S
% Thr: 9 0 0 0 0 17 0 17 17 0 9 0 0 9 17 % T
% Val: 34 42 17 0 0 0 34 9 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 9 9 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _