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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHD
All Species:
18.48
Human Site:
S52
Identified Species:
36.97
UniProt:
O14521
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14521
NP_002993.1
159
17043
S52
G
V
Q
H
I
H
L
S
P
S
H
H
S
G
S
Chimpanzee
Pan troglodytes
XP_508756
159
17009
S52
G
V
Q
H
I
H
L
S
P
S
H
H
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001093794
159
17136
S52
G
V
Q
H
I
H
L
S
P
R
H
H
S
G
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXV1
159
16995
S52
G
T
Q
H
I
H
L
S
P
S
H
H
S
G
S
Rat
Rattus norvegicus
Q6PCT8
159
16957
S52
G
T
Q
H
I
H
L
S
P
S
H
Q
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIS0
157
16417
A50
A
R
Q
S
H
G
G
A
P
Q
G
H
G
S
S
Frog
Xenopus laevis
Q6AZV0
152
16380
N47
S
Q
I
H
T
S
P
N
H
H
A
G
S
K
A
Zebra Danio
Brachydanio rerio
Q68FN7
158
16954
S51
A
R
I
H
A
T
P
S
N
Y
A
G
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI5
182
19282
A63
V
R
E
I
S
V
S
A
P
R
M
A
S
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62215
145
15746
K49
P
D
H
S
M
H
F
K
L
E
R
L
W
A
V
Sea Urchin
Strong. purpuratus
XP_792876
148
16234
L50
N
N
H
T
A
G
L
L
P
S
K
H
W
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGY6
166
17657
V56
T
V
N
D
P
V
E
V
P
P
P
S
P
S
H
Conservation
Percent
Protein Identity:
100
98.7
96.2
N.A.
N.A.
82.3
81.1
N.A.
N.A.
60.3
64.7
59.1
N.A.
29.6
N.A.
33.9
44.6
Protein Similarity:
100
100
97.4
N.A.
N.A.
88.6
87.4
N.A.
N.A.
67.9
74.8
71
N.A.
47.2
N.A.
45.9
63.5
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
86.6
N.A.
N.A.
26.6
13.3
33.3
N.A.
13.3
N.A.
6.6
26.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
86.6
N.A.
N.A.
33.3
26.6
33.3
N.A.
26.6
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
17
0
0
17
0
0
17
9
0
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
9
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
0
0
0
17
9
0
0
0
9
17
9
50
9
% G
% His:
0
0
17
59
9
50
0
0
9
9
42
50
0
0
9
% H
% Ile:
0
0
17
9
42
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
9
0
0
9
0
% K
% Leu:
0
0
0
0
0
0
50
9
9
0
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
9
9
0
0
0
0
9
9
0
0
0
0
9
0
% N
% Pro:
9
0
0
0
9
0
17
0
75
9
9
0
9
0
0
% P
% Gln:
0
9
50
0
0
0
0
0
0
9
0
9
0
0
0
% Q
% Arg:
0
25
0
0
0
0
0
0
0
17
9
0
0
0
0
% R
% Ser:
9
0
0
17
9
9
9
50
0
42
0
9
67
17
59
% S
% Thr:
9
17
0
9
9
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
34
0
0
0
17
0
9
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _