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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHD
All Species:
24.24
Human Site:
S59
Identified Species:
48.48
UniProt:
O14521
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14521
NP_002993.1
159
17043
S59
S
P
S
H
H
S
G
S
K
A
A
S
L
H
W
Chimpanzee
Pan troglodytes
XP_508756
159
17009
S59
S
P
S
H
H
S
G
S
K
A
A
S
L
H
W
Rhesus Macaque
Macaca mulatta
XP_001093794
159
17136
S59
S
P
R
H
H
S
G
S
K
A
A
S
L
H
W
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXV1
159
16995
S59
S
P
S
H
H
S
G
S
K
A
A
S
L
H
W
Rat
Rattus norvegicus
Q6PCT8
159
16957
S59
S
P
S
H
Q
S
G
S
K
A
A
S
L
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIS0
157
16417
S57
A
P
Q
G
H
G
S
S
K
A
A
S
L
H
W
Frog
Xenopus laevis
Q6AZV0
152
16380
A54
N
H
H
A
G
S
K
A
A
S
M
H
W
T
G
Zebra Danio
Brachydanio rerio
Q68FN7
158
16954
S58
S
N
Y
A
G
S
G
S
K
A
A
T
M
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI5
182
19282
G70
A
P
R
M
A
S
A
G
S
S
H
T
L
L
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62215
145
15746
V56
K
L
E
R
L
W
A
V
G
M
L
P
I
L
P
Sea Urchin
Strong. purpuratus
XP_792876
148
16234
A57
L
P
S
K
H
W
N
A
E
R
V
L
S
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGY6
166
17657
H63
V
P
P
P
S
P
S
H
G
S
Y
H
W
T
F
Conservation
Percent
Protein Identity:
100
98.7
96.2
N.A.
N.A.
82.3
81.1
N.A.
N.A.
60.3
64.7
59.1
N.A.
29.6
N.A.
33.9
44.6
Protein Similarity:
100
100
97.4
N.A.
N.A.
88.6
87.4
N.A.
N.A.
67.9
74.8
71
N.A.
47.2
N.A.
45.9
63.5
P-Site Identity:
100
100
93.3
N.A.
N.A.
100
93.3
N.A.
N.A.
66.6
6.6
60
N.A.
26.6
N.A.
0
20
P-Site Similarity:
100
100
93.3
N.A.
N.A.
100
93.3
N.A.
N.A.
73.3
26.6
73.3
N.A.
46.6
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
9
0
17
17
9
59
59
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
17
9
50
9
17
0
0
0
0
0
17
% G
% His:
0
9
9
42
50
0
0
9
0
0
9
17
0
59
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
9
0
0
9
0
0
9
0
59
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
9
0
0
0
0
0
9
9
59
17
0
% L
% Met:
0
0
0
9
0
0
0
0
0
9
9
0
9
0
0
% M
% Asn:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
75
9
9
0
9
0
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
17
9
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
50
0
42
0
9
67
17
59
9
25
0
50
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
17
0
17
0
% T
% Val:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
17
0
67
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _