KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHD
All Species:
29.39
Human Site:
T67
Identified Species:
58.79
UniProt:
O14521
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14521
NP_002993.1
159
17043
T67
K
A
A
S
L
H
W
T
S
E
R
V
V
S
V
Chimpanzee
Pan troglodytes
XP_508756
159
17009
T67
K
A
A
S
L
H
W
T
S
E
R
V
V
S
V
Rhesus Macaque
Macaca mulatta
XP_001093794
159
17136
T67
K
A
A
S
L
H
W
T
S
E
R
V
V
S
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXV1
159
16995
T67
K
A
A
S
L
H
W
T
S
E
R
V
V
S
V
Rat
Rattus norvegicus
Q6PCT8
159
16957
T67
K
A
A
S
L
H
W
T
S
E
R
V
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIS0
157
16417
T65
K
A
A
S
L
H
W
T
S
E
R
A
V
S
A
Frog
Xenopus laevis
Q6AZV0
152
16380
E62
A
S
M
H
W
T
G
E
R
A
L
S
V
A
L
Zebra Danio
Brachydanio rerio
Q68FN7
158
16954
T66
K
A
A
T
M
H
W
T
G
E
R
I
L
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI5
182
19282
T78
S
S
H
T
L
L
W
T
V
E
R
I
V
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62215
145
15746
A64
G
M
L
P
I
L
P
A
S
Y
F
I
H
G
P
Sea Urchin
Strong. purpuratus
XP_792876
148
16234
L65
E
R
V
L
S
I
G
L
I
G
I
I
P
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGY6
166
17657
D71
G
S
Y
H
W
T
F
D
R
V
V
A
A
G
L
Conservation
Percent
Protein Identity:
100
98.7
96.2
N.A.
N.A.
82.3
81.1
N.A.
N.A.
60.3
64.7
59.1
N.A.
29.6
N.A.
33.9
44.6
Protein Similarity:
100
100
97.4
N.A.
N.A.
88.6
87.4
N.A.
N.A.
67.9
74.8
71
N.A.
47.2
N.A.
45.9
63.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
86.6
6.6
60
N.A.
46.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
86.6
26.6
93.3
N.A.
66.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
59
59
0
0
0
0
9
0
9
0
17
9
17
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
9
0
67
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
17
0
9
9
0
0
0
17
0
% G
% His:
0
0
9
17
0
59
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
9
0
9
34
0
0
9
% I
% Lys:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
59
17
0
9
0
0
9
0
9
0
17
% L
% Met:
0
9
9
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
9
0
0
0
0
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
17
0
67
0
0
0
0
% R
% Ser:
9
25
0
50
9
0
0
0
59
0
0
9
0
67
0
% S
% Thr:
0
0
0
17
0
17
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
9
9
9
42
67
0
42
% V
% Trp:
0
0
0
0
17
0
67
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _