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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASTN1
All Species:
27.27
Human Site:
S274
Identified Species:
75
UniProt:
O14525
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14525
NP_004310.1
1302
144913
S274
Q
V
T
R
T
L
D
S
L
Q
G
C
N
E
K
Chimpanzee
Pan troglodytes
XP_514021
1382
153483
S362
Q
V
T
R
T
L
D
S
L
Q
G
C
N
E
K
Rhesus Macaque
Macaca mulatta
XP_001105186
1294
143940
S274
Q
V
T
R
T
L
D
S
L
Q
G
C
N
E
K
Dog
Lupus familis
XP_547451
1086
121066
L90
Y
E
Y
D
I
T
D
L
R
H
H
L
Q
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61137
1302
144909
S274
Q
V
T
R
T
L
D
S
L
Q
G
C
N
E
K
Rat
Rattus norvegicus
XP_002724926
1302
144888
S274
Q
V
T
R
T
L
D
S
L
Q
G
C
N
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515531
1305
145285
S285
Q
V
T
R
T
L
D
S
L
Q
G
C
N
D
K
Chicken
Gallus gallus
XP_426626
1355
150279
S336
Q
V
T
R
T
L
D
S
L
Q
G
C
N
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002660894
751
83839
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.1
81.9
N.A.
97.8
97.9
N.A.
87.6
88.3
N.A.
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.4
99.1
82.8
N.A.
99
99
N.A.
92.2
92.2
N.A.
51.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
78
0
0
0
% C
% Asp:
0
0
0
12
0
0
89
0
0
0
0
0
0
12
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
0
0
67
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% K
% Leu:
0
0
0
0
0
78
0
12
78
0
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
78
0
0
0
0
0
0
0
0
78
0
0
12
0
0
% Q
% Arg:
0
0
0
78
0
0
0
0
12
0
0
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% S
% Thr:
0
0
78
0
78
12
0
0
0
0
0
0
0
0
0
% T
% Val:
0
78
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _