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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FCHO1
All Species:
10.91
Human Site:
T418
Identified Species:
30
UniProt:
O14526
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14526
NP_001154829.1
889
96861
T418
R
P
R
S
A
P
R
T
S
S
C
A
E
R
L
Chimpanzee
Pan troglodytes
XP_001161856
915
100399
S437
R
D
F
L
E
P
D
S
G
T
C
P
E
V
D
Rhesus Macaque
Macaca mulatta
XP_001099245
809
88893
E350
S
D
S
D
S
E
D
E
E
P
K
K
Y
R
I
Dog
Lupus familis
XP_533878
896
97270
T425
R
P
R
S
A
P
R
T
S
S
C
A
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K285
873
95134
S410
G
K
P
Q
R
P
R
S
A
P
R
T
G
S
C
Rat
Rattus norvegicus
NP_001099539
560
59860
S101
R
P
R
S
A
P
R
S
S
C
T
E
K
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512954
688
75120
L229
N
A
V
K
E
I
H
L
Q
I
G
Q
V
H
E
Chicken
Gallus gallus
XP_001232744
865
94579
D402
S
S
D
S
D
S
E
D
D
E
P
R
R
F
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q502I9
848
93639
K389
N
N
G
T
H
Q
H
K
V
T
I
D
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.6
46.1
92
N.A.
86.1
54.1
N.A.
38.7
44.4
N.A.
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70.5
65.2
93.9
N.A.
91.7
57.3
N.A.
55
64.3
N.A.
58.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
93.3
N.A.
13.3
60
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
20
100
N.A.
26.6
73.3
N.A.
0
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
34
0
0
0
12
0
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
34
0
0
0
12
% C
% Asp:
0
23
12
12
12
0
23
12
12
0
0
12
0
0
12
% D
% Glu:
0
0
0
0
23
12
12
12
12
12
0
12
45
0
12
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
12
0
0
0
0
0
12
0
12
0
12
0
0
% G
% His:
0
0
0
0
12
0
23
0
0
0
0
0
0
12
12
% H
% Ile:
0
0
0
0
0
12
0
0
0
12
12
0
0
0
12
% I
% Lys:
0
12
0
12
0
0
0
12
0
0
12
12
12
12
12
% K
% Leu:
0
0
0
12
0
0
0
12
0
0
0
0
0
12
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
34
12
0
0
56
0
0
0
23
12
12
0
12
0
% P
% Gln:
0
0
0
12
0
12
0
0
12
0
0
12
0
0
0
% Q
% Arg:
45
0
34
0
12
0
45
0
0
0
12
12
12
23
0
% R
% Ser:
23
12
12
45
12
12
0
34
34
23
0
0
0
12
0
% S
% Thr:
0
0
0
12
0
0
0
23
0
23
12
12
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
12
0
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _