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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX2
All Species:
13.03
Human Site:
S366
Identified Species:
26.06
UniProt:
O14529
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14529
NP_056082
1424
154196
S366
E
D
P
S
E
D
D
S
I
K
D
S
L
G
T
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
Q428
A
R
R
K
G
K
D
Q
P
E
S
R
R
P
G
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
Q694
A
R
R
K
G
K
D
Q
P
E
S
R
R
P
G
Dog
Lupus familis
XP_543393
1527
166380
S451
E
D
P
S
E
D
D
S
I
K
D
S
L
G
T
Cat
Felis silvestris
Mouse
Mus musculus
P70298
1426
154685
S365
E
D
P
S
E
D
D
S
I
K
G
S
L
G
T
Rat
Rattus norvegicus
P53565
862
92341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
S465
E
D
H
S
E
D
D
S
V
K
D
S
L
G
T
Chicken
Gallus gallus
XP_415167
1214
132340
H306
R
L
L
K
D
I
Q
H
L
Q
S
S
L
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
N371
D
G
H
S
E
K
S
N
D
V
S
R
P
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
E550
P
V
P
A
E
D
D
E
E
D
E
D
Q
A
M
Honey Bee
Apis mellifera
XP_623857
1936
209316
A562
P
L
Q
R
A
S
T
A
S
P
H
G
G
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
D429
T
L
K
V
N
N
T
D
L
N
G
G
S
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.3
38
86.3
N.A.
83.9
28.5
N.A.
72.5
62.7
N.A.
57
N.A.
23.1
24
N.A.
27.1
Protein Similarity:
100
57.8
50.1
87.8
N.A.
87.6
40.7
N.A.
78.6
68.3
N.A.
67.9
N.A.
36
38.8
N.A.
44.5
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
0
N.A.
86.6
13.3
N.A.
13.3
N.A.
26.6
0
N.A.
6.6
P-Site Similarity:
100
13.3
13.3
100
N.A.
93.3
0
N.A.
93.3
33.3
N.A.
26.6
N.A.
40
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
9
0
0
9
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
34
0
0
9
42
59
9
9
9
25
9
0
0
0
% D
% Glu:
34
0
0
0
50
0
0
9
9
17
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
17
0
0
0
0
0
17
17
9
42
34
% G
% His:
0
0
17
0
0
0
0
9
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
25
0
0
0
0
0
0
% I
% Lys:
0
0
9
25
0
25
0
0
0
34
0
0
0
0
0
% K
% Leu:
0
25
9
0
0
0
0
0
17
0
0
0
42
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
9
0
9
0
9
0
0
0
0
0
% N
% Pro:
17
0
34
0
0
0
0
0
17
9
0
0
9
17
0
% P
% Gln:
0
0
9
0
0
0
9
17
0
9
0
0
9
9
0
% Q
% Arg:
9
17
17
9
0
0
0
0
0
0
0
25
17
0
0
% R
% Ser:
0
0
0
42
0
9
9
34
9
0
34
42
9
0
0
% S
% Thr:
9
0
0
0
0
0
17
0
0
0
0
0
0
0
34
% T
% Val:
0
9
0
9
0
0
0
0
9
9
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _