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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 6.06
Human Site: S616 Identified Species: 12.12
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 S616 K T S V A P L S I A N G T T P
Chimpanzee Pan troglodytes XP_527845 1515 165612 E687 E A I K S I L E Q A K R E L Q
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 E953 E A I K S I L E Q A K R E L Q
Dog Lupus familis XP_543393 1527 166380 S711 K N S T A P L S I T N G T A P
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 S616 K N S P A S V S I P N G T A S
Rat Rattus norvegicus P53565 862 92341 K166 L V R G S T W K D P W W N P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 H720 K S S P A P L H A A N G T G S
Chicken Gallus gallus XP_415167 1214 132340 V518 S S V P P N T V P P T T S P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 G618 S S L G C P S G R S S T G A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 R1011 Q S S V A Q H R E Q E R R S H
Honey Bee Apis mellifera XP_623857 1936 209316 H996 H L Q M R S E H E V S N D A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 A663 E S P P G P T A I A S P V K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 13.3 13.3 73.3 N.A. 53.3 0 N.A. 60 6.6 N.A. 6.6 N.A. 20 0 N.A. 20
P-Site Similarity: 100 26.6 26.6 73.3 N.A. 60 6.6 N.A. 66.6 20 N.A. 26.6 N.A. 40 13.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 42 0 0 9 9 42 0 0 0 34 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 9 % D
% Glu: 25 0 0 0 0 0 9 17 17 0 9 0 17 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 17 9 0 0 9 0 0 0 34 9 9 9 % G
% His: 9 0 0 0 0 0 9 17 0 0 0 0 0 0 9 % H
% Ile: 0 0 17 0 0 17 0 0 34 0 0 0 0 0 0 % I
% Lys: 34 0 0 17 0 0 0 9 0 0 17 0 0 9 0 % K
% Leu: 9 9 9 0 0 0 42 0 0 0 0 0 0 17 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 9 0 0 0 0 34 9 9 0 0 % N
% Pro: 0 0 9 34 9 42 0 0 9 25 0 9 0 17 25 % P
% Gln: 9 0 9 0 0 9 0 0 17 9 0 0 0 0 17 % Q
% Arg: 0 0 9 0 9 0 0 9 9 0 0 25 9 0 0 % R
% Ser: 17 42 42 0 25 17 9 25 0 9 25 0 9 9 17 % S
% Thr: 0 9 0 9 0 9 17 0 0 9 9 17 34 9 0 % T
% Val: 0 9 9 17 0 0 9 9 0 9 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 9 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _