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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 0.91
Human Site: S675 Identified Species: 1.82
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 S675 R P S L A T A S Q N G A P A L
Chimpanzee Pan troglodytes XP_527845 1515 165612 E783 K K P S A A P E A G A S A L P
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 E1049 K K P S A A P E A G A S A L P
Dog Lupus familis XP_543393 1527 166380 V778 Q N G A P A Y V K Q E D S S G
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 L680 T A S Q N G A L T C V K Q E D
Rat Rattus norvegicus P53565 862 92341 G213 A E R S Q L Q G P S A T A E Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 Y785 S Q N I V Q A Y I K Q E E G P
Chicken Gallus gallus XP_415167 1214 132340 F565 H N I G Q R V F G H Y V L G L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 K683 S S T P P F I K Q E E G I S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 M1169 F P N F S S L M A L Q Q Q V L
Honey Bee Apis mellifera XP_623857 1936 209316 H1167 K M E E A M R H A G S A F S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 P717 R H S L R S S P D S T H S F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 6.6 6.6 0 N.A. 13.3 0 N.A. 6.6 6.6 N.A. 6.6 N.A. 13.3 20 N.A. 20
P-Site Similarity: 100 20 20 20 N.A. 13.3 6.6 N.A. 20 13.3 N.A. 26.6 N.A. 33.3 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 34 25 25 0 34 0 25 17 25 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 9 % D
% Glu: 0 9 9 9 0 0 0 17 0 9 17 9 9 17 0 % E
% Phe: 9 0 0 9 0 9 0 9 0 0 0 0 9 9 0 % F
% Gly: 0 0 9 9 0 9 0 9 9 25 9 9 0 17 9 % G
% His: 9 9 0 0 0 0 0 9 0 9 0 9 0 0 0 % H
% Ile: 0 0 9 9 0 0 9 0 9 0 0 0 9 0 0 % I
% Lys: 25 17 0 0 0 0 0 9 9 9 0 9 0 0 0 % K
% Leu: 0 0 0 17 0 9 9 9 0 9 0 0 9 17 34 % L
% Met: 0 9 0 0 0 9 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 17 17 0 9 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 17 17 9 17 0 17 9 9 0 0 0 9 0 25 % P
% Gln: 9 9 0 9 17 9 9 0 17 9 17 9 17 0 0 % Q
% Arg: 17 0 9 0 9 9 9 0 0 0 0 0 0 0 0 % R
% Ser: 17 9 25 25 9 17 9 9 0 17 9 17 17 25 9 % S
% Thr: 9 0 9 0 0 9 0 0 9 0 9 9 0 0 0 % T
% Val: 0 0 0 0 9 0 9 9 0 0 9 9 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 9 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _