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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 3.64
Human Site: T1227 Identified Species: 7.27
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 T1227 E E N S T P L T T Q D K A Q V
Chimpanzee Pan troglodytes XP_527845 1515 165612 V1352 E G D S C D G V E A T E G P G
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 A1627 A T E G P G S A D T E E P K S
Dog Lupus familis XP_543393 1527 166380 T1330 E E S I T S P T T Q D K A Q V
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 P1234 G P L Q R A A P D R A L V K I
Rat Rattus norvegicus P53565 862 92341 A710 G P A E V T A A P A D R E E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 I1342 R G K T L I K I K Q E Q P E E
Chicken Gallus gallus XP_415167 1214 132340 E1062 L G Q R L F G E S I L G L T Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 K1241 I P H R F A V K Q E T T E P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 L1866 Y F A A A A I L G R S L A G I
Honey Bee Apis mellifera XP_623857 1936 209316 A1744 L A A L V G N A L K E Q C S G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 R1244 Q E R M D E E R V N D L K Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 13.3 0 73.3 N.A. 0 6.6 N.A. 6.6 0 N.A. 0 N.A. 6.6 0 N.A. 20
P-Site Similarity: 100 26.6 20 80 N.A. 20 20 N.A. 33.3 6.6 N.A. 20 N.A. 33.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 25 9 9 25 17 25 0 17 9 0 25 0 17 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 9 0 9 9 0 0 17 0 34 0 0 0 0 % D
% Glu: 25 25 9 9 0 9 9 9 9 9 25 17 17 17 17 % E
% Phe: 0 9 0 0 9 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 25 0 9 0 17 17 0 9 0 0 9 9 9 17 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 9 0 9 9 9 0 9 0 0 0 0 17 % I
% Lys: 0 0 9 0 0 0 9 9 9 9 0 17 9 17 0 % K
% Leu: 17 0 9 9 17 0 9 9 9 0 9 25 9 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 9 0 0 9 0 0 0 0 0 % N
% Pro: 0 25 0 0 9 9 9 9 9 0 0 0 17 17 0 % P
% Gln: 9 0 9 9 0 0 0 0 9 25 0 17 0 25 9 % Q
% Arg: 9 0 9 17 9 0 0 9 0 17 0 9 0 0 0 % R
% Ser: 0 0 9 17 0 9 9 0 9 0 9 0 0 9 9 % S
% Thr: 0 9 0 9 17 9 0 17 17 9 17 9 0 9 0 % T
% Val: 0 0 0 0 17 0 9 9 9 0 0 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _