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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 7.58
Human Site: T1293 Identified Species: 15.15
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 T1293 P L L P G G S T P D C P S L H
Chimpanzee Pan troglodytes XP_527845 1515 165612 G1390 Q T E P P P S G T P G P D D A
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 D1667 P D D A R D D D H E G G P A E
Dog Lupus familis XP_543393 1527 166380 S1396 L L L P G G T S P D C P S L Q
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 N1295 P F L S G T P N P D C P S L H
Rat Rattus norvegicus P53565 862 92341 P747 E D A G R S R P P P E G L A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 T1412 T Y S K A P A T P D C S S L H
Chicken Gallus gallus XP_415167 1214 132340 W1099 P F V R M Q L W L N D P H N V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 D1279 R S L N L L P D G P Q R N S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 S1923 P T L K R E R S D D Y Q D D L
Honey Bee Apis mellifera XP_623857 1936 209316 P1796 A G S I K R E P A E T P T A P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 E1345 A S V G G A A E S L L P I V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 20 6.6 73.3 N.A. 66.6 6.6 N.A. 46.6 13.3 N.A. 6.6 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 20 13.3 86.6 N.A. 66.6 6.6 N.A. 53.3 26.6 N.A. 13.3 N.A. 26.6 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 9 9 9 17 0 9 0 0 0 0 25 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % C
% Asp: 0 17 9 0 0 9 9 17 9 42 9 0 17 17 9 % D
% Glu: 9 0 9 0 0 9 9 9 0 17 9 0 0 0 9 % E
% Phe: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 17 34 17 0 9 9 0 17 17 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 25 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 17 42 0 9 9 9 0 9 9 9 0 9 34 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 0 9 0 0 9 9 0 % N
% Pro: 42 0 0 25 9 17 17 17 42 25 0 59 9 0 9 % P
% Gln: 9 0 0 0 0 9 0 0 0 0 9 9 0 0 9 % Q
% Arg: 9 0 0 9 25 9 17 0 0 0 0 9 0 0 0 % R
% Ser: 0 17 17 9 0 9 17 17 9 0 0 9 34 9 17 % S
% Thr: 9 17 0 0 0 9 9 17 9 0 9 0 9 0 0 % T
% Val: 0 0 17 0 0 0 0 0 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _