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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 17.88
Human Site: T305 Identified Species: 35.76
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 T305 S D Y E E I K T E L S I L K A
Chimpanzee Pan troglodytes XP_527845 1515 165612 K367 A D Y E E V K K E L N I L K S
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 K633 A D Y E E V K K E L N I L K S
Dog Lupus familis XP_543393 1527 166380 T390 S D Y E E I K T E L S I L K A
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 T304 A D Y E E I K T E L S I L R A
Rat Rattus norvegicus P53565 862 92341
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 T404 S D Y E E I K T E L S I L K A
Chicken Gallus gallus XP_415167 1214 132340 R245 Q R A E A A Q R E V E S L R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 T310 I D Y E E I K T E L S I L K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 I489 A R L D K Q Q I N E A L A E A
Honey Bee Apis mellifera XP_623857 1936 209316 R501 R D Y D D L K R E I N A L R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 R368 N D Y E E I K R E L N V L K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 66.6 66.6 100 N.A. 86.6 0 N.A. 100 20 N.A. 93.3 N.A. 6.6 33.3 N.A. 66.6
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 0 N.A. 100 40 N.A. 93.3 N.A. 53.3 80 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 9 0 9 9 0 0 0 0 9 9 9 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 75 0 17 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 75 67 0 0 0 84 9 9 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 50 0 9 0 9 0 59 0 0 0 % I
% Lys: 0 0 0 0 9 0 75 17 0 0 0 0 0 59 0 % K
% Leu: 0 0 9 0 0 9 0 0 0 67 0 9 84 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 9 0 34 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 9 17 0 0 0 0 0 0 0 0 % Q
% Arg: 9 17 0 0 0 0 0 25 0 0 0 0 0 25 0 % R
% Ser: 25 0 0 0 0 0 0 0 0 0 42 9 0 0 34 % S
% Thr: 0 0 0 0 0 0 0 42 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 17 0 0 0 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _