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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 8.79
Human Site: T610 Identified Species: 17.58
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 T610 Q K G G E P K T S V A P L S I
Chimpanzee Pan troglodytes XP_527845 1515 165612 A681 S E T G S D E A I K S I L E Q
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 A947 S E T G S D E A I K S I L E Q
Dog Lupus familis XP_543393 1527 166380 N705 Q K G G E S K N S T A P L S I
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 N610 Q K G G E S K N S P A S V S I
Rat Rattus norvegicus P53565 862 92341 V160 R P V K N E L V R G S T W K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 S714 Q K G S E A K S S P A P L H A
Chicken Gallus gallus XP_415167 1214 132340 S512 F F G A K S S S V P P N T V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 S612 Q R G D C K S S L G C P S G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 S1005 A S S L M K Q S S V A Q H R E
Honey Bee Apis mellifera XP_623857 1936 209316 L990 I L S E S G H L Q M R S E H E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 S657 L Q K K G K E S P P G P T A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 13.3 13.3 80 N.A. 66.6 0 N.A. 60 6.6 N.A. 20 N.A. 20 0 N.A. 13.3
P-Site Similarity: 100 33.3 33.3 80 N.A. 73.3 13.3 N.A. 66.6 20 N.A. 33.3 N.A. 33.3 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 9 0 17 0 0 42 0 0 9 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 9 0 17 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 17 0 9 34 9 25 0 0 0 0 0 9 17 17 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 50 42 9 9 0 0 0 17 9 0 0 9 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 9 17 0 % H
% Ile: 9 0 0 0 0 0 0 0 17 0 0 17 0 0 34 % I
% Lys: 0 34 9 17 9 25 34 0 0 17 0 0 0 9 0 % K
% Leu: 9 9 0 9 0 0 9 9 9 0 0 0 42 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 17 0 0 0 9 0 0 0 % N
% Pro: 0 9 0 0 0 9 0 0 9 34 9 42 0 0 9 % P
% Gln: 42 9 0 0 0 0 9 0 9 0 0 9 0 0 17 % Q
% Arg: 9 9 0 0 0 0 0 0 9 0 9 0 0 9 9 % R
% Ser: 17 9 17 9 25 25 17 42 42 0 25 17 9 25 0 % S
% Thr: 0 0 17 0 0 0 0 9 0 9 0 9 17 0 0 % T
% Val: 0 0 9 0 0 0 0 9 9 17 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _