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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX2
All Species:
16.97
Human Site:
Y1125
Identified Species:
33.94
UniProt:
O14529
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14529
NP_056082
1424
154196
Y1125
K
E
A
L
R
K
A
Y
Q
L
E
P
Y
P
S
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
Q1250
Y
S
Q
G
A
S
P
Q
P
Q
H
Q
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
R1525
Q
H
Q
L
K
K
P
R
V
V
L
A
P
E
E
Dog
Lupus familis
XP_543393
1527
166380
Y1228
K
E
A
L
K
K
A
Y
Q
L
E
P
Y
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P70298
1426
154685
Y1132
K
E
A
L
R
K
A
Y
Q
L
E
P
Y
P
S
Rat
Rattus norvegicus
P53565
862
92341
K608
L
K
R
A
Y
Q
Q
K
P
Y
P
S
P
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
Y1240
K
E
A
L
K
K
A
Y
Q
L
E
P
Y
P
S
Chicken
Gallus gallus
XP_415167
1214
132340
I960
T
D
Q
L
G
Q
G
I
S
Q
Q
P
T
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
E1139
P
R
V
V
L
A
A
E
E
K
E
A
L
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
F1764
K
E
A
L
R
L
A
F
A
L
D
P
Y
P
N
Honey Bee
Apis mellifera
XP_623857
1936
209316
F1642
K
E
A
L
R
L
A
F
A
L
D
P
Y
P
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
Y1142
K
D
H
L
K
A
S
Y
D
K
E
P
Y
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.3
38
86.3
N.A.
83.9
28.5
N.A.
72.5
62.7
N.A.
57
N.A.
23.1
24
N.A.
27.1
Protein Similarity:
100
57.8
50.1
87.8
N.A.
87.6
40.7
N.A.
78.6
68.3
N.A.
67.9
N.A.
36
38.8
N.A.
44.5
P-Site Identity:
100
0
13.3
93.3
N.A.
100
0
N.A.
93.3
26.6
N.A.
13.3
N.A.
66.6
66.6
N.A.
46.6
P-Site Similarity:
100
0
33.3
100
N.A.
100
20
N.A.
100
46.6
N.A.
26.6
N.A.
86.6
86.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
9
9
17
59
0
17
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
9
0
17
0
0
0
0
% D
% Glu:
0
50
0
0
0
0
0
9
9
0
50
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
59
9
0
0
34
42
0
9
0
17
0
0
0
17
17
% K
% Leu:
9
0
0
75
9
17
0
0
0
50
9
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% N
% Pro:
9
0
0
0
0
0
17
0
17
0
9
67
17
67
0
% P
% Gln:
9
0
25
0
0
17
9
9
34
17
9
9
0
0
0
% Q
% Arg:
0
9
9
0
34
0
0
9
0
0
0
0
0
9
0
% R
% Ser:
0
9
0
0
0
9
9
0
9
0
0
9
0
0
42
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
17
% T
% Val:
0
0
9
9
0
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
42
0
9
0
0
59
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _