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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX2 All Species: 16.97
Human Site: Y1125 Identified Species: 33.94
UniProt: O14529 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14529 NP_056082 1424 154196 Y1125 K E A L R K A Y Q L E P Y P S
Chimpanzee Pan troglodytes XP_527845 1515 165612 Q1250 Y S Q G A S P Q P Q H Q L K K
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 R1525 Q H Q L K K P R V V L A P E E
Dog Lupus familis XP_543393 1527 166380 Y1228 K E A L K K A Y Q L E P Y P S
Cat Felis silvestris
Mouse Mus musculus P70298 1426 154685 Y1132 K E A L R K A Y Q L E P Y P S
Rat Rattus norvegicus P53565 862 92341 K608 L K R A Y Q Q K P Y P S P K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 Y1240 K E A L K K A Y Q L E P Y P S
Chicken Gallus gallus XP_415167 1214 132340 I960 T D Q L G Q G I S Q Q P T P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 E1139 P R V V L A A E E K E A L R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 F1764 K E A L R L A F A L D P Y P N
Honey Bee Apis mellifera XP_623857 1936 209316 F1642 K E A L R L A F A L D P Y P N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780858 1460 163719 Y1142 K D H L K A S Y D K E P Y P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 38 86.3 N.A. 83.9 28.5 N.A. 72.5 62.7 N.A. 57 N.A. 23.1 24 N.A. 27.1
Protein Similarity: 100 57.8 50.1 87.8 N.A. 87.6 40.7 N.A. 78.6 68.3 N.A. 67.9 N.A. 36 38.8 N.A. 44.5
P-Site Identity: 100 0 13.3 93.3 N.A. 100 0 N.A. 93.3 26.6 N.A. 13.3 N.A. 66.6 66.6 N.A. 46.6
P-Site Similarity: 100 0 33.3 100 N.A. 100 20 N.A. 100 46.6 N.A. 26.6 N.A. 86.6 86.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 9 9 17 59 0 17 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 0 0 9 0 17 0 0 0 0 % D
% Glu: 0 50 0 0 0 0 0 9 9 0 50 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 9 9 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 59 9 0 0 34 42 0 9 0 17 0 0 0 17 17 % K
% Leu: 9 0 0 75 9 17 0 0 0 50 9 0 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % N
% Pro: 9 0 0 0 0 0 17 0 17 0 9 67 17 67 0 % P
% Gln: 9 0 25 0 0 17 9 9 34 17 9 9 0 0 0 % Q
% Arg: 0 9 9 0 34 0 0 9 0 0 0 0 0 9 0 % R
% Ser: 0 9 0 0 0 9 9 0 9 0 0 9 0 0 42 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 17 % T
% Val: 0 0 9 9 0 0 0 0 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 9 0 0 42 0 9 0 0 59 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _