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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX2
All Species:
7.27
Human Site:
Y753
Identified Species:
14.55
UniProt:
O14529
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14529
NP_056082
1424
154196
Y753
S
S
S
S
S
S
G
Y
S
G
Q
P
N
G
R
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
K861
A
E
E
A
G
G
G
K
E
K
G
S
G
G
S
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
K1127
A
E
E
T
G
G
G
K
E
K
G
S
G
G
S
Dog
Lupus familis
XP_543393
1527
166380
S856
S
S
S
S
S
S
Y
S
G
Q
P
N
G
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P70298
1426
154685
G758
S
S
S
S
S
Y
S
G
Q
P
N
G
R
A
W
Rat
Rattus norvegicus
P53565
862
92341
T291
E
V
D
T
I
E
L
T
R
Q
V
K
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
Y863
L
S
S
S
S
S
S
Y
S
S
L
P
S
G
R
Chicken
Gallus gallus
XP_415167
1214
132340
I643
S
D
D
A
I
K
N
I
L
E
Q
A
K
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
T761
S
L
S
S
S
S
S
T
S
M
P
R
P
W
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
G1247
P
P
S
G
P
G
T
G
A
G
A
P
P
T
A
Honey Bee
Apis mellifera
XP_623857
1936
209316
N1245
T
P
T
H
H
T
A
N
Q
R
P
L
K
A
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
Q795
S
K
T
H
A
M
M
Q
D
S
S
P
M
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.3
38
86.3
N.A.
83.9
28.5
N.A.
72.5
62.7
N.A.
57
N.A.
23.1
24
N.A.
27.1
Protein Similarity:
100
57.8
50.1
87.8
N.A.
87.6
40.7
N.A.
78.6
68.3
N.A.
67.9
N.A.
36
38.8
N.A.
44.5
P-Site Identity:
100
13.3
13.3
40
N.A.
33.3
0
N.A.
66.6
13.3
N.A.
40
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
26.6
26.6
40
N.A.
33.3
6.6
N.A.
73.3
20
N.A.
40
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
9
0
9
0
9
0
9
9
0
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
9
17
17
0
0
9
0
0
17
9
0
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
17
25
25
17
9
17
17
9
25
34
0
% G
% His:
0
0
0
17
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
0
17
0
17
0
9
17
17
0
% K
% Leu:
9
9
0
0
0
0
9
0
9
0
9
9
0
0
9
% L
% Met:
0
0
0
0
0
9
9
0
0
9
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
0
9
9
9
0
0
% N
% Pro:
9
17
0
0
9
0
0
0
0
9
25
34
17
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
17
17
17
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
9
0
9
9
9
17
% R
% Ser:
50
34
50
42
42
34
25
9
25
17
9
17
9
0
25
% S
% Thr:
9
0
17
17
0
9
9
17
0
0
0
0
0
17
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% W
% Tyr:
0
0
0
0
0
9
9
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _