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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC9
All Species:
51.82
Human Site:
T154
Identified Species:
71.25
UniProt:
O14530
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14530
NP_005774.2
226
26534
T154
A
L
L
K
D
G
K
T
Q
D
Y
V
V
G
F
Chimpanzee
Pan troglodytes
XP_001149127
226
26535
T154
A
L
L
K
D
G
K
T
Q
D
Y
V
V
G
F
Rhesus Macaque
Macaca mulatta
XP_001104184
226
26484
T154
A
L
V
K
D
G
K
T
Q
D
Y
V
V
G
F
Dog
Lupus familis
XP_531785
226
26528
T154
A
L
V
K
D
G
K
T
Q
D
Y
V
V
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ79
226
26241
T154
A
L
L
R
D
G
K
T
Q
D
Y
V
V
G
F
Rat
Rattus norvegicus
Q8K581
226
26253
T154
A
L
L
R
D
G
K
T
Q
D
Y
I
V
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506955
226
26451
T154
A
L
V
K
D
G
K
T
Q
D
Y
V
V
G
F
Chicken
Gallus gallus
XP_001232595
226
26335
T154
A
L
I
K
D
G
K
T
Q
D
Y
I
V
G
F
Frog
Xenopus laevis
NP_001080910
226
26401
T154
A
L
V
K
D
G
K
T
K
D
Y
I
V
G
F
Zebra Danio
Brachydanio rerio
Q6P268
239
27638
Y167
N
L
P
T
L
F
V
Y
R
D
G
E
M
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650026
216
25091
T145
A
L
V
K
D
S
K
T
K
D
F
I
V
G
F
Honey Bee
Apis mellifera
XP_624087
215
25115
T145
A
L
I
V
N
G
K
T
K
D
Y
I
V
G
F
Nematode Worm
Caenorhab. elegans
Q11183
208
24360
K125
F
I
H
V
N
A
E
K
V
H
F
L
T
T
R
Sea Urchin
Strong. purpuratus
XP_782876
224
25687
S145
A
L
I
K
D
G
K
S
K
D
Y
I
V
G
F
Poplar Tree
Populus trichocarpa
XP_002313888
213
24357
L143
L
V
L
P
T
L
A
L
I
K
N
A
K
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64628
211
24432
L140
K
I
V
V
L
P
T
L
A
L
I
K
N
T
K
Baker's Yeast
Sacchar. cerevisiae
Q04004
230
26604
Y160
V
L
P
F
V
V
G
Y
K
N
G
L
E
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
95.5
N.A.
89.8
88.5
N.A.
92.4
82.7
82.3
26.7
N.A.
51.7
46.4
38.9
52.6
Protein Similarity:
100
99.5
98.2
98.2
N.A.
94.2
93.8
N.A.
97.7
95.5
95.5
47.7
N.A.
69.9
68.1
64.5
73.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
93.3
86.6
80
13.3
N.A.
66.6
66.6
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
26.6
N.A.
93.3
93.3
33.3
100
Percent
Protein Identity:
45.1
N.A.
N.A.
45.5
32.6
N.A.
Protein Similarity:
67.7
N.A.
N.A.
69.4
54.3
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
71
0
0
0
0
6
6
0
6
0
0
6
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
65
0
0
0
0
77
0
0
0
0
6
% D
% Glu:
0
0
0
0
0
0
6
0
0
0
0
6
6
0
0
% E
% Phe:
6
0
0
6
0
6
0
0
0
0
12
0
0
0
71
% F
% Gly:
0
0
0
0
0
65
6
0
0
0
12
0
0
71
0
% G
% His:
0
0
6
0
0
0
0
0
0
6
0
0
0
0
0
% H
% Ile:
0
12
18
0
0
0
0
0
6
0
6
36
0
0
0
% I
% Lys:
6
0
0
53
0
0
71
6
30
6
0
6
6
12
6
% K
% Leu:
6
83
30
0
12
6
0
12
0
6
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
6
0
0
0
12
0
0
0
0
6
6
0
6
0
0
% N
% Pro:
0
0
12
6
0
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
48
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
6
0
0
0
0
0
6
% R
% Ser:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
6
6
0
6
65
0
0
0
0
6
12
0
% T
% Val:
6
6
36
18
6
6
6
0
6
0
0
36
71
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
65
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _