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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC9
All Species:
38.79
Human Site:
Y219
Identified Species:
53.33
UniProt:
O14530
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14530
NP_005774.2
226
26534
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Chimpanzee
Pan troglodytes
XP_001149127
226
26535
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Rhesus Macaque
Macaca mulatta
XP_001104184
226
26484
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Dog
Lupus familis
XP_531785
226
26528
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ79
226
26241
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Rat
Rattus norvegicus
Q8K581
226
26253
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506955
226
26451
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
E
D
D
Chicken
Gallus gallus
XP_001232595
226
26335
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Frog
Xenopus laevis
NP_001080910
226
26401
Y219
K
T
I
R
G
K
K
Y
D
S
D
S
D
D
D
Zebra Danio
Brachydanio rerio
Q6P268
239
27638
G232
S
A
N
T
H
R
D
G
E
E
D
S
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650026
216
25091
Honey Bee
Apis mellifera
XP_624087
215
25115
Nematode Worm
Caenorhab. elegans
Q11183
208
24360
E200
K
I
I
R
S
G
V
E
E
Y
D
N
E
E
D
Sea Urchin
Strong. purpuratus
XP_782876
224
25687
Y215
K
I
I
K
G
G
R
Y
N
D
S
D
S
D
L
Poplar Tree
Populus trichocarpa
XP_002313888
213
24357
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64628
211
24432
A204
R
R
N
V
R
Q
S
A
R
S
D
S
D
S
E
Baker's Yeast
Sacchar. cerevisiae
Q04004
230
26604
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
95.5
N.A.
89.8
88.5
N.A.
92.4
82.7
82.3
26.7
N.A.
51.7
46.4
38.9
52.6
Protein Similarity:
100
99.5
98.2
98.2
N.A.
94.2
93.8
N.A.
97.7
95.5
95.5
47.7
N.A.
69.9
68.1
64.5
73.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
100
26.6
N.A.
0
0
33.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
46.6
N.A.
0
0
60
53.3
Percent
Protein Identity:
45.1
N.A.
N.A.
45.5
32.6
N.A.
Protein Similarity:
67.7
N.A.
N.A.
69.4
54.3
N.A.
P-Site Identity:
0
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
46.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
6
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
53
6
71
6
59
59
65
% D
% Glu:
0
0
0
0
0
0
0
6
12
6
0
0
12
12
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
59
12
0
6
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
65
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
65
0
0
6
0
53
53
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
6
0
0
6
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
6
0
59
6
6
6
0
6
0
0
0
0
0
0
% R
% Ser:
6
0
0
0
6
0
6
0
0
59
6
65
6
6
0
% S
% Thr:
0
53
0
6
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
6
0
0
6
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _