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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOCS6 All Species: 27.88
Human Site: S161 Identified Species: 51.11
UniProt: O14544 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14544 NP_004223.2 535 59528 S161 R V K A L V H S S S P S P A L
Chimpanzee Pan troglodytes XP_512211 535 59559 S161 R V K A L V H S S S P S P A L
Rhesus Macaque Macaca mulatta XP_001095656 535 59456 S161 R V K A L V H S S S P S P A L
Dog Lupus familis XP_533377 535 59510 S161 R V K A L V H S S S P S P A L
Cat Felis silvestris
Mouse Mus musculus Q9JLY0 533 58875 G161 L V H A A S P G P V N G V R K
Rat Rattus norvegicus XP_001063512 547 60813 L173 V R K E L R E L Q P K E L R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506079 518 56852 H160 V R V K A L V H S A H P S P A
Chicken Gallus gallus NP_001120784 534 59819 S160 K V K A L V H S S N P S P A L
Frog Xenopus laevis NP_001086732 533 60367 S160 K V K A L V H S T S P S P V L
Zebra Danio Brachydanio rerio XP_687041 519 57925 S161 K V K A M V H S P N P S P S L
Tiger Blowfish Takifugu rubipres NP_001116334 531 59124 S162 M V H S P S P S P N L K G V R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624532 358 41531
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780887 391 44540 P33 T S T R I S R P K T G Q V D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.5 94.5 N.A. 84.3 82.4 N.A. 77.5 90.2 81.6 70.4 72.7 N.A. 30 N.A. 30
Protein Similarity: 100 99.6 98.8 96.4 N.A. 88.7 87.1 N.A. 83.3 95.5 91.4 81.6 83.5 N.A. 46.1 N.A. 45.7
P-Site Identity: 100 100 100 100 N.A. 13.3 13.3 N.A. 6.6 86.6 80 66.6 13.3 N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 13.3 13.3 N.A. 20 100 93.3 93.3 26.6 N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 62 16 0 0 0 0 8 0 0 0 39 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % D
% Glu: 0 0 0 8 0 0 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 8 8 8 0 0 % G
% His: 0 0 16 0 0 0 54 8 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 24 0 62 8 0 0 0 0 8 0 8 8 0 0 8 % K
% Leu: 8 0 0 0 54 8 0 8 0 0 8 0 8 0 54 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 24 8 0 0 0 8 % N
% Pro: 0 0 0 0 8 0 16 8 24 8 54 8 54 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 31 16 0 8 0 8 8 0 0 0 0 0 0 16 8 % R
% Ser: 0 8 0 8 0 24 0 62 47 39 0 54 8 8 0 % S
% Thr: 8 0 8 0 0 0 0 0 8 8 0 0 0 0 0 % T
% Val: 16 70 8 0 0 54 8 0 0 8 0 0 16 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _