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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOCS6 All Species: 31.21
Human Site: S245 Identified Species: 57.22
UniProt: O14544 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14544 NP_004223.2 535 59528 S245 R S Y C L D S S S P M E V S A
Chimpanzee Pan troglodytes XP_512211 535 59559 S245 R S Y C L D S S S P M E V S A
Rhesus Macaque Macaca mulatta XP_001095656 535 59456 S245 R S Y C L D S S S P M E V S A
Dog Lupus familis XP_533377 535 59510 S245 R S Y C L D G S S P M E V S A
Cat Felis silvestris
Mouse Mus musculus Q9JLY0 533 58875 S243 R S C C L D T S S P M E V S A
Rat Rattus norvegicus XP_001063512 547 60813 S257 R S C C L D T S S P M E V S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506079 518 56852 L235 L E E G M Y P L E G S R S C C
Chicken Gallus gallus NP_001120784 534 59819 S244 R S Y C L D S S S P M E V S T
Frog Xenopus laevis NP_001086732 533 60367 S244 R A F C L D R S S P M E I S T
Zebra Danio Brachydanio rerio XP_687041 519 57925 P236 Q S F C L D G P S P M E V G D
Tiger Blowfish Takifugu rubipres NP_001116334 531 59124 S244 S F C L D S S S P M E V V T E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624532 358 41531 N75 Y D P S A V Q N N K S T I S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780887 391 44540 E108 C D V N D N A E I F E E R L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.5 94.5 N.A. 84.3 82.4 N.A. 77.5 90.2 81.6 70.4 72.7 N.A. 30 N.A. 30
Protein Similarity: 100 99.6 98.8 96.4 N.A. 88.7 87.1 N.A. 83.3 95.5 91.4 81.6 83.5 N.A. 46.1 N.A. 45.7
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 0 93.3 66.6 60 20 N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 6.6 93.3 86.6 73.3 26.6 N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 8 0 0 0 0 0 0 0 47 % A
% Cys: 8 0 24 70 0 0 0 0 0 0 0 0 0 8 8 % C
% Asp: 0 16 0 0 16 70 0 0 0 0 0 0 0 0 16 % D
% Glu: 0 8 8 0 0 0 0 8 8 0 16 77 0 0 8 % E
% Phe: 0 8 16 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 16 0 0 8 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 16 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 8 0 0 8 70 0 0 8 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 8 70 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 8 8 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 8 8 8 70 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 62 0 0 0 0 0 8 0 0 0 0 8 8 0 0 % R
% Ser: 8 62 0 8 0 8 39 70 70 0 16 0 8 70 0 % S
% Thr: 0 0 0 0 0 0 16 0 0 0 0 8 0 8 16 % T
% Val: 0 0 8 0 0 8 0 0 0 0 0 8 70 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 39 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _