Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOCS6 All Species: 32.12
Human Site: S311 Identified Species: 58.89
UniProt: O14544 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14544 NP_004223.2 535 59528 S311 H D D V P P L S P L L P P M Q
Chimpanzee Pan troglodytes XP_512211 535 59559 S311 H D D V P P L S P L L P P M Q
Rhesus Macaque Macaca mulatta XP_001095656 535 59456 S311 H D D V P P L S P L L P P M Q
Dog Lupus familis XP_533377 535 59510 S311 H D D A P P L S P L L P P M Q
Cat Felis silvestris
Mouse Mus musculus Q9JLY0 533 58875 S309 H D D A P P L S P L L P P M Q
Rat Rattus norvegicus XP_001063512 547 60813 S323 H D D A P P L S P L L P P M Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506079 518 56852 P298 P P L S P L L P P L Q N N P I
Chicken Gallus gallus NP_001120784 534 59819 S310 H S D V P P L S P L L P P M Q
Frog Xenopus laevis NP_001086732 533 60367 S309 H N D V P P L S P L L P P V Q
Zebra Danio Brachydanio rerio XP_687041 519 57925 S299 P L F S P S L S P L S T N D I
Tiger Blowfish Takifugu rubipres NP_001116334 531 59124 L308 V P P P L S P L L P P M M S N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624532 358 41531 R138 K Q I T N K F R T D I N H E N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780887 391 44540 I171 K N M K N S T I S L G E E Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.5 94.5 N.A. 84.3 82.4 N.A. 77.5 90.2 81.6 70.4 72.7 N.A. 30 N.A. 30
Protein Similarity: 100 99.6 98.8 96.4 N.A. 88.7 87.1 N.A. 83.3 95.5 91.4 81.6 83.5 N.A. 46.1 N.A. 45.7
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 26.6 93.3 86.6 33.3 0 N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 26.6 93.3 100 33.3 0 N.A. 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 47 62 0 0 0 0 0 0 8 0 0 0 8 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 8 8 0 % E
% Phe: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 62 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 8 0 0 0 16 % I
% Lys: 16 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 8 0 8 8 77 8 8 85 62 0 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 8 8 54 0 % M
% Asn: 0 16 0 0 16 0 0 0 0 0 0 16 16 0 16 % N
% Pro: 16 16 8 8 77 62 8 8 77 8 8 62 62 8 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 62 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 16 0 24 0 70 8 0 8 0 0 8 0 % S
% Thr: 0 0 0 8 0 0 8 0 8 0 0 8 0 0 0 % T
% Val: 8 0 0 39 0 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _