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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAFD1
All Species:
22.73
Human Site:
S256
Identified Species:
50
UniProt:
O14545
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14545
NP_001137378.1
582
64841
S256
Q
N
E
G
Q
A
S
S
V
A
E
Q
D
F
W
Chimpanzee
Pan troglodytes
XP_509385
599
66897
S273
Q
N
E
G
Q
A
S
S
V
A
E
Q
D
F
W
Rhesus Macaque
Macaca mulatta
XP_001109743
582
64932
S256
Q
N
E
G
Q
A
S
S
V
A
E
Q
D
F
W
Dog
Lupus familis
XP_534682
583
65437
S256
Q
N
E
G
Q
A
R
S
V
A
E
Q
D
F
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDK1
580
64264
S256
Q
N
E
G
Q
A
T
S
M
V
E
Q
G
F
W
Rat
Rattus norvegicus
Q99MM4
576
63788
S256
Q
N
E
G
Q
A
S
S
M
V
E
Q
G
F
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506558
621
70191
S260
Q
N
E
S
S
L
H
S
S
S
L
N
P
E
I
Chicken
Gallus gallus
NP_001006191
320
36525
H27
P
A
A
N
F
T
I
H
E
I
H
C
S
R
N
Frog
Xenopus laevis
NP_001085457
606
68318
R267
K
D
K
V
A
K
Y
R
D
W
Q
K
D
S
N
Zebra Danio
Brachydanio rerio
NP_001082984
565
63934
D262
Q
T
E
G
D
L
E
D
P
R
Q
E
G
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789301
754
83873
E305
N
R
D
L
D
E
S
E
L
D
L
W
E
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
84
N.A.
76.2
75.2
N.A.
50.2
26.9
28.8
34
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
96.3
97.4
91
N.A.
84.1
83.1
N.A.
63.9
39
45.8
50.1
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
26.6
0
6.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
33.3
0
40
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
55
0
0
0
37
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
10
0
19
0
0
10
10
10
0
0
46
0
10
% D
% Glu:
0
0
73
0
0
10
10
10
10
0
55
10
10
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
55
0
% F
% Gly:
0
0
0
64
0
0
0
0
0
0
0
0
28
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% I
% Lys:
10
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
10
0
19
0
0
10
0
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% M
% Asn:
10
64
0
10
0
0
0
0
0
0
0
10
0
0
19
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% P
% Gln:
73
0
0
0
55
0
0
0
0
0
19
55
0
0
0
% Q
% Arg:
0
10
0
0
0
0
10
10
0
10
0
0
0
10
0
% R
% Ser:
0
0
0
10
10
0
46
64
10
10
0
0
10
19
0
% S
% Thr:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
37
19
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
64
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _