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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRAFD1 All Species: 20.91
Human Site: S278 Identified Species: 46
UniProt: O14545 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14545 NP_001137378.1 582 64841 S278 Q S H G G P R S L S D I K G A
Chimpanzee Pan troglodytes XP_509385 599 66897 S295 Q S H G G P R S L S D I K G A
Rhesus Macaque Macaca mulatta XP_001109743 582 64932 S278 Q S H G G P S S L S D I K G A
Dog Lupus familis XP_534682 583 65437 A278 Q S F E G S S A L N D M K G A
Cat Felis silvestris
Mouse Mus musculus Q3UDK1 580 64264 S278 P A R A G P T S L G D I K G A
Rat Rattus norvegicus Q99MM4 576 63788 S278 P A R A G P T S L G D I K G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506558 621 70191 S286 S S P S R G F S R A Q D K V Y
Chicken Gallus gallus NP_001006191 320 36525 S48 C K E S V P K S E M K N H I E
Frog Xenopus laevis NP_001085457 606 68318 T289 V E A D S P S T Q T E T E L G
Zebra Danio Brachydanio rerio NP_001082984 565 63934 S284 M G R T P A H S N L T S Q L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789301 754 83873 S328 R R L N S Q V S Q S A L W D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 95.6 84 N.A. 76.2 75.2 N.A. 50.2 26.9 28.8 34 N.A. N.A. N.A. N.A. 24.4
Protein Similarity: 100 96.3 97.4 91 N.A. 84.1 83.1 N.A. 63.9 39 45.8 50.1 N.A. N.A. N.A. N.A. 40.8
P-Site Identity: 100 100 93.3 53.3 N.A. 60 60 N.A. 20 13.3 6.6 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 73.3 N.A. 66.6 66.6 N.A. 26.6 20 33.3 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 19 0 10 0 10 0 10 10 0 0 0 64 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 55 10 0 10 0 % D
% Glu: 0 10 10 10 0 0 0 0 10 0 10 0 10 0 10 % E
% Phe: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 28 55 10 0 0 0 19 0 0 0 55 10 % G
% His: 0 0 28 0 0 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 46 0 10 0 % I
% Lys: 0 10 0 0 0 0 10 0 0 0 10 0 64 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 55 10 0 10 0 19 0 % L
% Met: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 10 10 0 10 0 0 0 % N
% Pro: 19 0 10 0 10 64 0 0 0 0 0 0 0 0 0 % P
% Gln: 37 0 0 0 0 10 0 0 19 0 10 0 10 0 0 % Q
% Arg: 10 10 28 0 10 0 19 0 10 0 0 0 0 0 0 % R
% Ser: 10 46 0 19 19 10 28 82 0 37 0 10 0 0 10 % S
% Thr: 0 0 0 10 0 0 19 10 0 10 10 10 0 0 0 % T
% Val: 10 0 0 0 10 0 10 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _