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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAFD1
All Species:
16.06
Human Site:
S491
Identified Species:
35.33
UniProt:
O14545
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14545
NP_001137378.1
582
64841
S491
P
K
L
S
N
S
D
S
Q
D
I
Q
G
R
N
Chimpanzee
Pan troglodytes
XP_509385
599
66897
S508
L
K
L
S
N
S
D
S
Q
D
I
Q
G
R
N
Rhesus Macaque
Macaca mulatta
XP_001109743
582
64932
S491
L
K
L
N
N
S
D
S
Q
D
I
Q
G
R
N
Dog
Lupus familis
XP_534682
583
65437
S491
L
K
L
N
N
L
D
S
Q
D
S
R
G
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDK1
580
64264
S490
L
K
L
N
N
S
D
S
Q
D
I
R
G
Q
M
Rat
Rattus norvegicus
Q99MM4
576
63788
D491
L
N
N
S
G
S
Q
D
I
R
G
R
I
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506558
621
70191
Q523
K
P
N
N
L
E
A
Q
D
L
R
G
R
S
R
Chicken
Gallus gallus
NP_001006191
320
36525
L236
Y
E
E
Q
N
A
N
L
D
H
M
L
A
L
S
Frog
Xenopus laevis
NP_001085457
606
68318
D490
D
R
L
L
A
S
D
D
L
F
P
Q
G
R
T
Zebra Danio
Brachydanio rerio
NP_001082984
565
63934
A475
E
E
L
L
Q
Q
T
A
H
G
W
Q
R
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789301
754
83873
A637
L
S
Q
F
D
N
D
A
L
L
T
R
E
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
84
N.A.
76.2
75.2
N.A.
50.2
26.9
28.8
34
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
96.3
97.4
91
N.A.
84.1
83.1
N.A.
63.9
39
45.8
50.1
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
93.3
86.6
66.6
N.A.
66.6
20
N.A.
0
6.6
40
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
80
N.A.
86.6
26.6
N.A.
6.6
40
46.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
19
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
64
19
19
46
0
0
0
10
0
% D
% Glu:
10
19
10
0
0
10
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
10
10
55
10
10
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
37
0
10
0
0
% I
% Lys:
10
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
55
0
64
19
10
10
0
10
19
19
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
10
19
37
55
10
10
0
0
0
0
0
0
0
37
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
10
10
10
10
10
10
46
0
0
46
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
10
37
19
55
19
% R
% Ser:
0
10
0
28
0
55
0
46
0
0
10
0
0
10
19
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _