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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAFD1
All Species:
9.09
Human Site:
T414
Identified Species:
20
UniProt:
O14545
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14545
NP_001137378.1
582
64841
T414
L
D
S
Q
P
Q
E
T
S
P
E
L
P
R
R
Chimpanzee
Pan troglodytes
XP_509385
599
66897
T431
V
D
S
Q
P
Q
E
T
S
P
E
L
P
R
R
Rhesus Macaque
Macaca mulatta
XP_001109743
582
64932
N414
L
D
S
Q
P
Q
E
N
S
P
E
L
P
R
R
Dog
Lupus familis
XP_534682
583
65437
T414
Q
D
F
Q
P
P
E
T
S
P
D
L
P
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDK1
580
64264
N413
A
Q
D
S
Q
P
E
N
T
S
A
E
L
S
R
Rat
Rattus norvegicus
Q99MM4
576
63788
R414
Q
D
S
Q
P
E
D
R
S
P
E
L
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506558
621
70191
M446
Q
D
N
L
Q
K
D
M
S
P
E
L
T
R
R
Chicken
Gallus gallus
NP_001006191
320
36525
R159
D
A
G
L
H
A
L
R
D
I
R
N
Q
L
R
Frog
Xenopus laevis
NP_001085457
606
68318
H413
Q
N
R
I
E
Q
P
H
D
R
N
I
R
P
V
Zebra Danio
Brachydanio rerio
NP_001082984
565
63934
G398
S
S
S
S
P
V
E
G
D
V
L
I
P
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789301
754
83873
S560
L
G
Q
A
D
D
V
S
G
R
A
Q
Y
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
84
N.A.
76.2
75.2
N.A.
50.2
26.9
28.8
34
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
96.3
97.4
91
N.A.
84.1
83.1
N.A.
63.9
39
45.8
50.1
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
93.3
93.3
66.6
N.A.
13.3
66.6
N.A.
46.6
6.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
20
80
N.A.
66.6
6.6
20
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
10
0
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
55
10
0
10
10
19
0
28
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
55
0
0
0
46
10
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
19
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
28
0
0
19
0
0
10
0
0
0
10
55
10
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
19
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
55
19
10
0
0
55
0
0
46
10
0
% P
% Gln:
37
10
10
46
19
37
0
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
19
0
19
10
0
10
46
82
% R
% Ser:
10
10
46
19
0
0
0
10
55
10
0
0
10
19
0
% S
% Thr:
0
0
0
0
0
0
0
28
10
0
0
0
10
0
0
% T
% Val:
10
0
0
0
0
10
10
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _