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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAFD1
All Species:
2.12
Human Site:
T437
Identified Species:
4.67
UniProt:
O14545
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14545
NP_001137378.1
582
64841
T437
S
S
G
Y
L
D
D
T
K
Q
E
T
A
N
G
Chimpanzee
Pan troglodytes
XP_509385
599
66897
I454
S
S
G
Y
L
D
D
I
K
Q
E
T
A
N
G
Rhesus Macaque
Macaca mulatta
XP_001109743
582
64932
I437
S
S
G
Y
L
D
D
I
K
Q
E
T
A
N
G
Dog
Lupus familis
XP_534682
583
65437
I437
S
S
G
Y
M
D
D
I
K
Q
E
T
A
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDK1
580
64264
D436
L
S
S
G
Y
M
D
D
V
K
P
E
S
V
K
Rat
Rattus norvegicus
Q99MM4
576
63788
V437
S
S
G
Y
M
D
D
V
K
Q
E
S
V
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506558
621
70191
I469
P
A
C
Y
L
D
D
I
K
P
E
V
A
N
R
Chicken
Gallus gallus
NP_001006191
320
36525
E182
W
R
M
P
R
V
L
E
R
Q
T
Y
S
S
C
Frog
Xenopus laevis
NP_001085457
606
68318
C436
S
S
N
I
L
I
P
C
E
F
C
S
V
L
M
Zebra Danio
Brachydanio rerio
NP_001082984
565
63934
D421
N
V
L
F
H
H
Q
D
K
C
D
L
R
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789301
754
83873
S583
R
T
G
T
K
P
V
S
K
K
F
T
N
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
84
N.A.
76.2
75.2
N.A.
50.2
26.9
28.8
34
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
96.3
97.4
91
N.A.
84.1
83.1
N.A.
63.9
39
45.8
50.1
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
93.3
93.3
80
N.A.
13.3
66.6
N.A.
53.3
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
26.6
80
N.A.
60
26.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
46
0
0
% A
% Cys:
0
0
10
0
0
0
0
10
0
10
10
0
0
0
10
% C
% Asp:
0
0
0
0
0
55
64
19
0
0
10
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
55
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
55
10
0
0
0
0
0
0
0
0
0
0
46
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
10
0
37
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
73
19
0
0
0
19
10
% K
% Leu:
10
0
10
0
46
0
10
0
0
0
0
10
0
10
0
% L
% Met:
0
0
10
0
19
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
0
10
37
0
% N
% Pro:
10
0
0
10
0
10
10
0
0
10
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
55
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
0
0
0
10
0
0
0
10
0
10
% R
% Ser:
55
64
10
0
0
0
0
10
0
0
0
19
19
19
0
% S
% Thr:
0
10
0
10
0
0
0
10
0
0
10
46
0
0
0
% T
% Val:
0
10
0
0
0
10
10
10
10
0
0
10
19
10
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
55
10
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _