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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAFD1
All Species:
20
Human Site:
Y153
Identified Species:
44
UniProt:
O14545
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14545
NP_001137378.1
582
64841
Y153
V
A
I
P
P
N
A
Y
D
E
S
W
G
Q
D
Chimpanzee
Pan troglodytes
XP_509385
599
66897
Y170
V
A
I
P
S
N
A
Y
D
E
S
W
G
Q
D
Rhesus Macaque
Macaca mulatta
XP_001109743
582
64932
Y153
V
A
I
P
P
N
A
Y
D
E
S
W
G
Q
D
Dog
Lupus familis
XP_534682
583
65437
Y153
V
A
V
P
P
N
A
Y
D
E
S
W
G
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDK1
580
64264
Y153
A
A
I
P
P
E
A
Y
D
E
P
W
S
Q
D
Rat
Rattus norvegicus
Q99MM4
576
63788
Y153
A
A
V
P
P
E
A
Y
D
E
P
W
S
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506558
621
70191
N151
A
R
S
R
P
R
P
N
Y
E
N
E
G
A
D
Chicken
Gallus gallus
NP_001006191
320
36525
Frog
Xenopus laevis
NP_001085457
606
68318
P164
D
L
L
H
A
I
L
P
S
R
F
Y
R
N
P
Zebra Danio
Brachydanio rerio
NP_001082984
565
63934
W153
G
P
Q
S
P
G
A
W
F
E
T
H
S
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789301
754
83873
R192
S
A
T
M
P
S
A
R
N
V
N
L
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
84
N.A.
76.2
75.2
N.A.
50.2
26.9
28.8
34
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
96.3
97.4
91
N.A.
84.1
83.1
N.A.
63.9
39
45.8
50.1
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
93.3
100
93.3
N.A.
73.3
66.6
N.A.
26.6
0
0
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
100
100
N.A.
73.3
73.3
N.A.
33.3
0
13.3
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
64
0
0
10
0
73
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
55
0
0
0
0
0
64
% D
% Glu:
0
0
0
0
0
19
0
0
0
73
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
0
46
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
37
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
0
0
10
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
37
0
10
10
0
19
0
0
10
0
% N
% Pro:
0
10
0
55
73
0
10
10
0
0
19
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
55
0
% Q
% Arg:
0
10
0
10
0
10
0
10
0
10
0
0
10
0
0
% R
% Ser:
10
0
10
10
10
10
0
0
10
0
37
0
37
10
10
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
37
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
55
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _