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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRAFD1 All Species: 26.67
Human Site: Y300 Identified Species: 58.67
UniProt: O14545 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14545 NP_001137378.1 582 64841 Y300 C E F C E E L Y P E E L L I D
Chimpanzee Pan troglodytes XP_509385 599 66897 Y317 C E F C E E L Y P E E L L I D
Rhesus Macaque Macaca mulatta XP_001109743 582 64932 Y300 C E F C E E L Y P E E L L I D
Dog Lupus familis XP_534682 583 65437 Y300 C E F C E E L Y P E E L L I D
Cat Felis silvestris
Mouse Mus musculus Q3UDK1 580 64264 Y300 C E F C E E L Y P E E L L I D
Rat Rattus norvegicus Q99MM4 576 63788 Y300 C E F C E E L Y P E E L L I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506558 621 70191 Y323 C E F C E E L Y P E E D L I L
Chicken Gallus gallus NP_001006191 320 36525 C65 H V Q V T C K C S M K V E K S
Frog Xenopus laevis NP_001085457 606 68318 F306 C E F C E K L F P A E D L I L
Zebra Danio Brachydanio rerio NP_001082984 565 63934 A301 T S K N C T T A P P K T H T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789301 754 83873 F357 C E F C N K A F P L E D L I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 95.6 84 N.A. 76.2 75.2 N.A. 50.2 26.9 28.8 34 N.A. N.A. N.A. N.A. 24.4
Protein Similarity: 100 96.3 97.4 91 N.A. 84.1 83.1 N.A. 63.9 39 45.8 50.1 N.A. N.A. N.A. N.A. 40.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 0 66.6 6.6 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 13.3 80 20 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % A
% Cys: 82 0 0 82 10 10 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 55 % D
% Glu: 0 82 0 0 73 64 0 0 0 64 82 0 10 0 0 % E
% Phe: 0 0 82 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % I
% Lys: 0 0 10 0 0 19 10 0 0 0 19 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 73 0 0 10 0 55 82 0 28 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 91 10 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 10 % S
% Thr: 10 0 0 0 10 10 10 0 0 0 0 10 0 10 0 % T
% Val: 0 10 0 10 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _