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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX7A2L All Species: 9.39
Human Site: S49 Identified Species: 20.67
UniProt: O14548 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14548 NP_004709.2 114 12615 S49 P T K L T S D S T V Y D Y A G
Chimpanzee Pan troglodytes XP_001138018 111 12043 Y49 L T S D S T V Y D Y A G K N K
Rhesus Macaque Macaca mulatta XP_001110575 114 12652 S49 P T K L T S D S T V Y D Y A G
Dog Lupus familis XP_532946 114 12734 F49 P T K L S S D F T A Y D Y A G
Cat Felis silvestris
Mouse Mus musculus Q61387 111 12381 T49 T K L T S S V T A Y D Y S G K
Rat Rattus norvegicus P35171 83 9334 N26 T S R R H F E N K V P E K Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513319 90 9879 Q33 T G H D F A A Q N R V P E L Q
Chicken Gallus gallus XP_419450 193 21646 L126 T T K L A S D L P A T D S F L
Frog Xenopus laevis NP_001089916 114 12550 A49 T K L A T E S A A T S Y L G D
Zebra Danio Brachydanio rerio NP_956268 115 12573 S49 P T K L V S E S S A T V E Y M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHS2 89 9883 Y32 K D Q I E K G Y F E I R K V Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.3 97.3 89.4 N.A. 88.5 34.2 N.A. 59.6 41.4 72.8 64.3 N.A. 29.8 N.A. N.A. N.A.
Protein Similarity: 100 84.2 100 96.4 N.A. 92.9 49.1 N.A. 67.5 50.2 85 83.4 N.A. 44.7 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 80 N.A. 6.6 6.6 N.A. 0 40 6.6 40 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 86.6 N.A. 20 40 N.A. 6.6 40 13.3 53.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 10 10 19 28 10 0 0 28 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 19 0 0 37 0 10 0 10 37 0 0 10 % D
% Glu: 0 0 0 0 10 10 19 0 0 10 0 10 19 0 0 % E
% Phe: 0 0 0 0 10 10 0 10 10 0 0 0 0 10 0 % F
% Gly: 0 10 0 0 0 0 10 0 0 0 0 10 0 19 28 % G
% His: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 10 19 46 0 0 10 0 0 10 0 0 0 28 0 28 % K
% Leu: 10 0 19 46 0 0 0 10 0 0 0 0 10 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % N
% Pro: 37 0 0 0 0 0 0 0 10 0 10 10 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 0 0 10 19 % Q
% Arg: 0 0 10 10 0 0 0 0 0 10 0 10 0 0 0 % R
% Ser: 0 10 10 0 28 55 10 28 10 0 10 0 19 0 0 % S
% Thr: 46 55 0 10 28 10 0 10 28 10 19 0 0 0 0 % T
% Val: 0 0 0 0 10 0 19 0 0 28 10 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 19 0 19 28 19 28 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _