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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAPDHS
All Species:
21.52
Human Site:
S220
Identified Species:
47.33
UniProt:
O14556
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14556
NP_055179.1
408
44501
S220
P
G
S
M
N
I
V
S
N
A
S
C
T
T
N
Chimpanzee
Pan troglodytes
XP_512590
408
44488
S220
P
G
S
M
N
I
V
S
N
A
S
C
T
T
N
Rhesus Macaque
Macaca mulatta
XP_001095332
409
44578
S221
P
G
S
M
N
I
V
S
N
A
S
C
T
T
N
Dog
Lupus familis
XP_533693
404
44075
S216
P
A
S
M
K
V
V
S
N
A
S
C
T
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64467
440
47638
S252
P
G
S
M
T
I
V
S
N
A
S
C
T
T
N
Rat
Rattus norvegicus
Q9ESV6
432
46689
S244
P
G
S
M
T
V
V
S
N
A
S
C
T
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P00356
333
35685
N165
L
A
K
V
I
H
D
N
F
G
I
V
E
G
L
Frog
Xenopus laevis
P51469
333
35679
N165
L
A
K
V
I
N
D
N
F
G
I
V
E
G
L
Zebra Danio
Brachydanio rerio
Q5MJ86
335
36089
N167
L
A
K
V
I
H
D
N
F
G
I
E
E
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07487
332
35351
N164
L
A
K
V
I
N
D
N
F
E
I
V
E
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P17330
341
36441
N173
L
A
K
V
I
N
D
N
F
G
I
I
E
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.3
84.3
N.A.
76.8
79.1
N.A.
N.A.
56.8
56.6
64.2
N.A.
57.5
N.A.
57.5
N.A.
Protein Similarity:
100
99.2
97.3
91.1
N.A.
83.8
86.1
N.A.
N.A.
67.1
67.6
71.8
N.A.
67.4
N.A.
68.3
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
86.6
N.A.
N.A.
0
0
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
0
0
0
0
0
55
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% C
% Asp:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
10
46
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% F
% Gly:
0
46
0
0
0
0
0
0
0
37
0
0
0
37
0
% G
% His:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
46
37
0
0
0
0
46
10
0
0
0
% I
% Lys:
0
0
46
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% L
% Met:
0
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
28
28
0
46
55
0
0
0
0
0
55
% N
% Pro:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
55
0
0
0
0
55
0
0
55
0
0
0
0
% S
% Thr:
0
0
0
0
19
0
0
0
0
0
0
0
55
55
0
% T
% Val:
0
0
0
46
0
19
55
0
0
0
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _