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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAPDHS All Species: 22.73
Human Site: Y113 Identified Species: 50
UniProt: O14556 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14556 NP_055179.1 408 44501 Y113 D P F I D P E Y M V Y M F K Y
Chimpanzee Pan troglodytes XP_512590 408 44488 Y113 D P F I D P E Y M V Y M F K Y
Rhesus Macaque Macaca mulatta XP_001095332 409 44578 Y114 D P F I D P E Y M V Y M F K Y
Dog Lupus familis XP_533693 404 44075 Y109 D P F I D P E Y M V Y M F K Y
Cat Felis silvestris
Mouse Mus musculus Q64467 440 47638 Y145 D P F I D P E Y M V Y M F K Y
Rat Rattus norvegicus Q9ESV6 432 46689 Y137 D P F I D P E Y M V Y M F K Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P00356 333 35685 K59 G H F K G T V K A E N G K L V
Frog Xenopus laevis P51469 333 35679 K59 G R F K G T V K A E N G K L I
Zebra Danio Brachydanio rerio Q5MJ86 335 36089 M61 R Y K G E V H M E D G K L I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07487 332 35351 A58 G R F K G T V A A E G G F L V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P17330 341 36441 L67 V A H E G D Y L L V A K E G K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.3 84.3 N.A. 76.8 79.1 N.A. N.A. 56.8 56.6 64.2 N.A. 57.5 N.A. 57.5 N.A.
Protein Similarity: 100 99.2 97.3 91.1 N.A. 83.8 86.1 N.A. N.A. 67.1 67.6 71.8 N.A. 67.4 N.A. 68.3 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 6.6 0 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 6.6 6.6 N.A. 13.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 28 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 55 0 0 0 55 10 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 0 55 0 10 28 0 0 10 0 0 % E
% Phe: 0 0 82 0 0 0 0 0 0 0 0 0 64 0 0 % F
% Gly: 28 0 0 10 37 0 0 0 0 0 19 28 0 10 0 % G
% His: 0 10 10 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 55 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 10 28 0 0 0 19 0 0 0 19 19 55 10 % K
% Leu: 0 0 0 0 0 0 0 10 10 0 0 0 10 28 0 % L
% Met: 0 0 0 0 0 0 0 10 55 0 0 55 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % N
% Pro: 0 55 0 0 0 55 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 28 0 0 64 0 0 0 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 55 0 0 55 0 0 0 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _