KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP33
All Species:
10
Human Site:
S622
Identified Species:
27.5
UniProt:
O14559
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14559
NP_443180.2
1287
137213
S622
T
R
A
P
P
Q
P
S
G
S
R
P
D
T
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099117
1287
137381
S622
T
R
A
P
P
Q
P
S
G
G
R
P
D
T
V
Dog
Lupus familis
XP_541687
914
96938
G294
L
P
P
Q
L
C
P
G
H
V
G
S
W
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80YF9
1305
139782
S646
S
R
A
P
P
Q
P
S
G
S
R
P
D
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519071
486
54071
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPD0
1940
216005
F700
L
E
M
K
S
M
A
F
A
G
G
R
D
S
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIS1
1843
204199
A799
S
F
V
Q
A
S
H
A
H
A
S
K
E
L
T
Honey Bee
Apis mellifera
XP_624644
1581
174986
S640
S
R
S
V
S
H
D
S
Y
F
D
H
L
A
D
Nematode Worm
Caenorhab. elegans
Q20498
759
87002
P139
G
S
I
I
T
C
Y
P
V
L
K
F
L
E
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
64.1
N.A.
90.5
N.A.
N.A.
33.6
N.A.
32.8
N.A.
N.A.
26.3
27.3
22.4
N.A.
Protein Similarity:
100
N.A.
98.8
65.8
N.A.
92.4
N.A.
N.A.
35.4
N.A.
42.8
N.A.
N.A.
37.9
41.1
34.4
N.A.
P-Site Identity:
100
N.A.
93.3
6.6
N.A.
93.3
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
0
13.3
0
N.A.
P-Site Similarity:
100
N.A.
93.3
6.6
N.A.
100
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
26.6
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
12
0
12
12
12
12
0
0
0
12
12
% A
% Cys:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
12
0
45
0
12
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
0
12
12
0
% E
% Phe:
0
12
0
0
0
0
0
12
0
12
0
12
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
12
34
23
23
0
0
0
0
% G
% His:
0
0
0
0
0
12
12
0
23
0
0
12
0
0
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
12
12
0
0
0
% K
% Leu:
23
0
0
0
12
0
0
0
0
12
0
0
23
12
0
% L
% Met:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
12
34
34
0
45
12
0
0
0
34
0
12
0
% P
% Gln:
0
0
0
23
0
34
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
45
0
0
0
0
0
0
0
0
34
12
0
0
0
% R
% Ser:
34
12
12
0
23
12
0
45
0
23
12
12
0
12
12
% S
% Thr:
23
0
0
0
12
0
0
0
0
0
0
0
0
34
12
% T
% Val:
0
0
12
12
0
0
0
0
12
12
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _