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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB561D2 All Species: 22.73
Human Site: Y216 Identified Species: 62.5
UniProt: O14569 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14569 NP_008953.1 222 23974 Y216 Q V S N A Y L Y R K R I Q P _
Chimpanzee Pan troglodytes XP_001148197 282 30753 P276 Q I S R S Y L P R K K M E M _
Rhesus Macaque Macaca mulatta XP_001100118 222 23946 Y216 Q V S N A Y L Y R K R I Q P _
Dog Lupus familis XP_541875 222 24046 Y216 Q V S N A Y L Y R K R I Q P _
Cat Felis silvestris
Mouse Mus musculus Q9WUE3 222 24168 Y216 Q V S N A Y L Y R K R I Q P _
Rat Rattus norvegicus Q641Y1 222 24105 Y216 Q V S N A Y L Y R K R I Q P _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518374 222 24505 Y216 Q V S N A Y L Y R K R I Q P _
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q503V1 253 27887 V214 A A F G A L V V W I A T R S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798124 176 19984
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.4 98.1 94.5 N.A. 95.5 95.9 N.A. 86 N.A. N.A. 20.1 N.A. N.A. N.A. N.A. 29.2
Protein Similarity: 100 48.2 98.1 96.8 N.A. 97.3 97.3 N.A. 91.4 N.A. N.A. 38.7 N.A. N.A. N.A. N.A. 45.5
P-Site Identity: 100 42.8 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 78.5 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 20 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 78 0 0 0 0 0 12 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 12 0 67 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 78 12 0 0 0 0 % K
% Leu: 0 0 0 0 0 12 78 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 12 0 % M
% Asn: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 12 0 0 0 0 0 67 0 % P
% Gln: 78 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % Q
% Arg: 0 0 0 12 0 0 0 0 78 0 67 0 12 0 0 % R
% Ser: 0 0 78 0 12 0 0 0 0 0 0 0 0 12 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % T
% Val: 0 67 0 0 0 0 12 12 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 78 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % _