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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIT
All Species:
18.18
Human Site:
Y818
Identified Species:
44.44
UniProt:
O14578
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14578
NP_009105.1
2027
231431
Y818
E
L
R
Q
Q
K
F
Y
L
E
T
Q
A
G
K
Chimpanzee
Pan troglodytes
XP_001158928
2027
231356
Y818
E
L
R
Q
Q
K
F
Y
L
E
T
Q
A
G
K
Rhesus Macaque
Macaca mulatta
XP_001085560
2069
236690
Y860
E
L
R
Q
Q
K
F
Y
L
E
T
Q
A
G
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P49025
2055
235371
Y859
E
L
R
Q
Q
K
F
Y
L
E
T
Q
A
G
K
Rat
Rattus norvegicus
Q7TT49
1713
194869
E634
K
E
L
E
A
R
L
E
D
A
V
A
E
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513915
588
68657
Chicken
Gallus gallus
XP_415277
2027
231609
Y818
E
L
R
Q
Q
K
F
Y
L
E
T
Q
A
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919786
1119
126974
Q40
E
N
A
E
L
N
R
Q
N
F
Y
L
S
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
A558
K
E
E
E
L
D
G
A
M
Q
K
N
D
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199576
1369
153558
M290
N
Q
Q
M
D
T
S
M
A
D
C
H
N
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.6
N.A.
N.A.
94.5
24.2
N.A.
23.6
90.2
N.A.
35.9
N.A.
23.1
N.A.
N.A.
26.4
Protein Similarity:
100
99.9
97.7
N.A.
N.A.
96.5
42.3
N.A.
26.7
95.9
N.A.
45.4
N.A.
41.4
N.A.
N.A.
41.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
0
N.A.
0
100
N.A.
6.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
20
N.A.
0
100
N.A.
26.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
10
10
10
0
10
50
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
10
10
0
0
10
0
0
% D
% Glu:
60
20
10
30
0
0
0
10
0
50
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
50
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
50
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
0
50
0
0
0
0
10
0
0
20
50
% K
% Leu:
0
50
10
0
20
0
10
0
50
0
0
10
0
0
20
% L
% Met:
0
0
0
10
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
10
0
0
10
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
50
50
0
0
10
0
10
0
50
0
0
10
% Q
% Arg:
0
0
50
0
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
50
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _