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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPE
All Species:
21.82
Human Site:
S77
Identified Species:
36.92
UniProt:
O14579
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14579
NP_009194.2
308
34482
S77
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
V
Chimpanzee
Pan troglodytes
XP_001137184
331
36905
S77
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
V
Rhesus Macaque
Macaca mulatta
XP_001114807
308
34452
S77
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
V
Dog
Lupus familis
XP_852205
308
34510
S77
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
V
Cat
Felis silvestris
Mouse
Mus musculus
O89079
308
34549
S77
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
V
Rat
Rattus norvegicus
NP_001099546
166
18646
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515042
306
34392
S75
L
D
E
I
K
A
N
S
C
A
E
L
Q
A
V
Chicken
Gallus gallus
Q5ZIK9
308
34350
A77
L
D
E
I
K
A
N
A
S
P
E
L
Q
A
V
Frog
Xenopus laevis
NP_001085327
299
33968
L82
V
R
M
F
A
E
Y
L
S
N
E
S
R
R
D
Zebra Danio
Brachydanio rerio
NP_001007365
300
34014
L83
V
R
M
F
A
E
Y
L
S
S
E
G
K
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393328
300
34733
A81
L
Q
P
L
K
M
L
A
D
Y
F
A
N
P
C
Nematode Worm
Caenorhab. elegans
O62246
292
32785
F77
A
V
R
R
Y
A
E
F
R
N
N
P
A
A
K
Sea Urchin
Strong. purpuratus
XP_787154
291
33045
L83
V
R
L
F
A
D
Y
L
A
N
P
D
R
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64748
293
32640
V75
A
A
T
P
L
Q
A
V
K
L
L
A
M
Y
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
99
94.1
N.A.
90.5
49.6
N.A.
82.4
78.9
77.2
76.6
N.A.
N.A.
62.3
36
49
Protein Similarity:
100
92.7
99.6
97.4
N.A.
95.4
51.2
N.A.
91.5
91.8
90.2
89.6
N.A.
N.A.
77.9
59.4
66.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
73.3
73.3
6.6
6.6
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
80
93.3
26.6
26.6
N.A.
N.A.
26.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
22
22
8
15
43
8
0
15
8
58
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
50
0
0
0
8
0
0
8
0
0
8
0
0
22
% D
% Glu:
0
0
50
0
0
15
8
0
0
0
65
0
0
0
0
% E
% Phe:
0
0
0
22
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
58
0
0
0
8
0
0
0
8
0
8
% K
% Leu:
58
0
8
8
8
0
8
22
0
8
8
50
0
0
8
% L
% Met:
0
0
15
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
22
8
0
8
0
0
% N
% Pro:
0
0
8
8
0
36
0
0
0
43
8
8
0
8
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
50
0
0
% Q
% Arg:
0
22
8
8
0
0
0
0
8
0
0
0
15
22
0
% R
% Ser:
0
0
0
0
0
0
36
43
22
8
0
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
22
8
0
0
0
0
0
8
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
22
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _