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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPE
All Species:
26.67
Human Site:
Y127
Identified Species:
45.13
UniProt:
O14579
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14579
NP_009194.2
308
34482
Y127
L
L
M
A
A
S
I
Y
L
H
D
Q
N
P
D
Chimpanzee
Pan troglodytes
XP_001137184
331
36905
Y127
L
L
M
A
A
S
I
Y
L
H
D
Q
N
P
D
Rhesus Macaque
Macaca mulatta
XP_001114807
308
34452
Y127
L
L
M
A
A
S
V
Y
L
H
D
Q
N
P
D
Dog
Lupus familis
XP_852205
308
34510
Y127
L
L
M
A
A
S
I
Y
F
H
D
Q
N
P
D
Cat
Felis silvestris
Mouse
Mus musculus
O89079
308
34549
Y127
L
L
M
A
A
S
I
Y
F
H
D
Q
N
P
D
Rat
Rattus norvegicus
NP_001099546
166
18646
L19
S
S
G
E
V
D
E
L
F
D
V
K
N
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515042
306
34392
Y125
L
L
M
A
A
S
I
Y
F
H
D
H
N
P
D
Chicken
Gallus gallus
Q5ZIK9
308
34350
Y127
L
L
M
A
A
S
I
Y
F
H
D
K
N
P
D
Frog
Xenopus laevis
NP_001085327
299
33968
H132
D
A
A
L
R
A
L
H
Q
G
D
S
L
E
C
Zebra Danio
Brachydanio rerio
NP_001007365
300
34014
H133
D
A
A
L
R
T
L
H
Q
G
E
S
L
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393328
300
34733
I131
N
L
E
A
A
L
R
I
L
R
N
V
D
H
L
Nematode Worm
Caenorhab. elegans
O62246
292
32785
S127
Q
D
A
F
R
A
V
S
R
F
E
G
L
E
A
Sea Urchin
Strong. purpuratus
XP_787154
291
33045
H133
L
T
P
V
S
N
L
H
T
G
H
N
F
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64748
293
32640
N125
F
M
H
E
E
D
Y
N
E
T
L
K
H
T
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
99
94.1
N.A.
90.5
49.6
N.A.
82.4
78.9
77.2
76.6
N.A.
N.A.
62.3
36
49
Protein Similarity:
100
92.7
99.6
97.4
N.A.
95.4
51.2
N.A.
91.5
91.8
90.2
89.6
N.A.
N.A.
77.9
59.4
66.2
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
6.6
N.A.
86.6
86.6
6.6
0
N.A.
N.A.
26.6
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
86.6
93.3
26.6
26.6
N.A.
N.A.
40
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
22
58
58
15
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
15
8
0
0
0
15
0
0
0
8
58
0
8
0
58
% D
% Glu:
0
0
8
15
8
0
8
0
8
0
15
0
0
22
0
% E
% Phe:
8
0
0
8
0
0
0
0
36
8
0
0
8
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
22
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
22
0
50
8
8
8
8
8
% H
% Ile:
0
0
0
0
0
0
43
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
0
% K
% Leu:
58
58
0
15
0
8
22
8
29
0
8
0
22
0
8
% L
% Met:
0
8
50
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
8
0
0
8
8
58
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
50
0
% P
% Gln:
8
0
0
0
0
0
0
0
15
0
0
36
0
0
0
% Q
% Arg:
0
0
0
0
22
0
8
0
8
8
0
0
0
0
0
% R
% Ser:
8
8
0
0
8
50
0
8
0
0
0
15
0
0
0
% S
% Thr:
0
8
0
0
0
8
0
0
8
8
0
0
0
8
0
% T
% Val:
0
0
0
8
8
0
15
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _